Results 51 to 60 of about 588,242 (306)

Superoxide Dismutases in Pancreatic Cancer

open access: yesAntioxidants, 2017
The incidence of pancreatic cancer is increasing as the population ages but treatment advancements continue to lag far behind. The majority of pancreatic cancer patients have a K-ras oncogene mutation causing a shift in the redox state of the cell ...
Justin G. Wilkes   +2 more
doaj   +1 more source

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

open access: yes, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R.   +5 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chloramphenicol mediates superoxide production in Photosystem II and enhances its photodamage in isolated membrane particles

open access: yesFrontiers in Plant Science, 2016
Chloramphenicol is an inhibitor of protein synthesis, which is frequently used to decouple photodamage and protein synthesis dependent repair of Photosystem II during the process of photoinhibition.
Ateeq Ur Rehman   +2 more
doaj   +1 more source

Scavenging of superoxide by a membrane-bound superoxide oxidase [PDF]

open access: yesNature Chemical Biology, 2018
Superoxide is a reactive oxygen species produced during aerobic metabolism in mitochondria and prokaryotes. It causes damage to lipids, proteins and DNA and is implicated in cancer, cardiovascular disease, neurodegenerative disorders and aging. As protection, cells express soluble superoxide dismutases, disproportionating superoxide to oxygen and ...
Lundgren, Camilla A K   +9 more
openaire   +3 more sources

Zinc and Copper Levels in Patients with Primary Hypertension and Normotension [PDF]

open access: yes, 2015
One of the causes of primary hypertension is an exposure to free radicals. The formation of free radicals in the body can be prevented by taking antioxidants. Zinc and copper are cofactors of endogenous antioxidant enzyme superoxide dismutase. This study
Adriani, M. (Merryana)   +2 more
core  

Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]

open access: yes, 2015
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi   +38 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Effect of vitamin E supplementation on superoxide and malondialdehyde generation in acute celphos poisoning

open access: yesArchives of Medicine and Health Sciences, 2017
Introduction: Aluminum phosphide is one of the most commonly used grain fumigants and aluminum phosphide poisoning (ALP) has been reported as the most common cause of acute poisoning in India.
C Biwas, J Bala, Simmi Kharb
doaj   +1 more source

Modeling the Energy Landscape of Side Reactions in the Cytochrome bc1 Complex

open access: yesFrontiers in Chemistry, 2021
Much of the metabolic molecular machinery responsible for energy transduction processes in living organisms revolves around a series of electron and proton transfer processes.
Peter Husen, Ilia A. Solov’yov
doaj   +1 more source

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