Results 11 to 20 of about 442,139 (308)
Scavenging of superoxide by a membrane-bound superoxide oxidase [PDF]
Nature Chemical Biology, 2018 Superoxide is a reactive oxygen species produced during aerobic metabolism in mitochondria and prokaryotes. It causes damage to lipids, proteins and DNA and is implicated in cancer, cardiovascular disease, neurodegenerative disorders and aging. As protection, cells express soluble superoxide dismutases, disproportionating superoxide to oxygen and ...
Lundgren, Camilla A K +9 more
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Zinc Supplementation Combats Tuberculosis by Reverting Back to Normal Compartmentalized State of Iron and Hence Increasing Blood Hemoglobin Concentration [PDF]
Indian Journal of Medical Biochemistry, 2023 Aim and background: To acquire iron (Fe), Mycobacterium tuberculosis (Mtb) expresses high-affinity Fe+3-specific siderophores for scavenging Fe from host insoluble and protein-bound iron-like transferrin, lactoferrin, ferritin, and hemoglobin−haptoglobin.
Dipak Kumar Chattopadhyay
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Superoxide, superoxide dismutase and ischemic injury.
Current opinion in investigational drugs (London, England : 2000), 2002 Oxidative stress results from an oxidant/antioxidant imbalance: an excess of oxidants relative to the antioxidant capacity. Recent evidence strongly suggests that oxidant stress plays a major role in several aspects of ischemia and reperfusion. Immunohistochemical and biochemical evidence demonstrate the significant role of reactive oxygen species, in ...
Salvemini, Daniela, CUZZOCREA, Salvatore
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Pharmaceuticals, 2023 Pimpinella anisum L., or anise, is a plant that, besides its nutritional value, has been used in traditional medical practices and described in many cultures in the Mediterranean region. A possible reason for anise’s therapeutic value is that it contains
Miriam Rossi +7 more
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The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite
Biomolecules, 2021 While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H2DCF, so we concluded that
André Luís Condeles +1 more
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Functional interactions between NADPH oxidase 5 and actin
Frontiers in Cell and Developmental Biology, 2023 NADPH oxidase 5 (NOX5) is a transmembrane oxidative signaling enzyme which produces superoxide in response to intracellular calcium flux. Increasing evidence indicates that NOX5 is involved in a variety of physiological processes as well as human disease,
Samantha M. Richter +3 more
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Antioxidants, 2020 Lipid hydroperoxides play an important role in various pathophysiological processes. Therefore, a simple model for organic hydroperoxides could be helpful to monitor the biologic effects of endogenous and exogenous compounds.
Anton Misak +5 more
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Foods, 2022 Soybean is a rich source of high-quality proteins and an excellent food source of bioactive peptides. A tripeptide, Leu–Ser–Trp (LSW), was previously identified from soybean as an angiotensin-converting enzyme inhibitory peptide.
Hongbing Fan +3 more
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Effect of 7-nitroindazoleon superoxide production and MnSOD activity in threat brain following kainate-induced neurotoxicity [PDF]
Archives of Biological Sciences, 2008 We investigated the effect of 7-nitroindazole (7-NI), a selective neuronal nitric oxide synthase inhibitor in vivo, on superoxide concentration as well its influence on mitochondrial MnSOD activity since this activity is associated with the production of
Radenović Lidija
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Antioxidants, 2021 Superoxide radical anion (O2•−) and its derivatives regulate numerous physiological and pathological processes, which are extensively studied. The aim of our work was to utilize KO2 as a source of O2•− and the electron paramagnetic resonance (EPR) spin ...
Anton Misak +8 more
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