Results 41 to 50 of about 562,973 (359)
Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function [PDF]
, 2015 Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO ...
Cassidy, Aedin +4 more
core +1 more source
Frontiers in Genetics, 2016 It has become clear that mitochondrial reactive oxygen species (mtROS) are not simply villains and mitochondria the hapless targets of their attacks. Rather, it appears that mitochondrial dysfunction itself and the signaling function of mtROS can have ...
Siegfried Hekimi, Ying Wang, Alycia Noe
doaj +1 more source
Antioxidants, 2021 Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2 diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are associated with low-grade inflammation.
Alain Menzel +5 more
doaj +1 more source
Pulse radiolysis studies on superoxide reductase from Treponema pallidum [PDF]
FEBS Letters, Elsevier, 2001, 497, pp.171-3, 2015 Superoxide reductases (SORs) are small metalloenzymes, which catalyze reduction of O2*- to H2O2. The reaction of the enzyme from Treponema pallidum with superoxide was studied by pulse radiolysis methods. The first step is an extremely fast bi-molecular reaction of the ferrous center with O2, with a rate constant of 6 x 10 (8) M(-1) s(-1).
arxiv +1 more source
Species-level variability in extracellular production rates of reactive oxygen species by diatoms
Frontiers in Chemistry, 2016 Biological production and decay of the reactive oxygen species (ROS) hydrogen peroxide (H2O2) and superoxide (O2-) likely have significant effects on the cycling of trace metals and carbon in marine systems. In this study, extracellular production rates
Robin Julie Schneider +5 more
doaj +1 more source
Radical pairs and superoxide amplification can explain magnetic field effects on planarian regeneration [PDF]
arXiv, 2023 Weak magnetic field exposure can affect many biological processes across a wide range of living organisms. Recently, it has been observed that weak magnetic fields can modulate reactive oxygen species (ROS) concentration, affecting regeneration in planaria.
arxiv
Structure of superoxide reductase bound to ferrocyanide and active site expansion upon X-ray-induced photo-reduction [PDF]
Structure, 2004, 12, pp.1729-40, 2015 Some sulfate-reducing and microaerophilic bacteria rely on the enzyme superoxide reductase (SOR) to eliminate the toxic superoxide anion radical (O2*-). SOR catalyses the one-electron reduction of O2*- to hydrogen peroxide at a nonheme ferrous iron center. The structures of Desulfoarculus baarsii SOR (mutant E47A) alone and in complex with ferrocyanide
arxiv +1 more source
S-adenosylmethionine and superoxide dismutase 1 synergistically counteract Alzheimer's disease features progression in tgCRND8 mice [PDF]
, 2017 Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer's Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism ...
Cavallaro, Rosaria A +4 more
core +2 more sources
Molecules, 2013 Novel antioxidants have been synthesized and characterized by their chemical properties as antioxidants with high superoxide scavenging activity. (2R,3R)-diphenylethylenediamine is a spacer in antioxidants, and we synthesized targets 11a and 11b by ...
Shigeki Kobayashi, Sachi Kanai
doaj +1 more source
What Is the Relevance of Murburn Concept in Thalassemia and Respiratory Diseases?
Thalassemia Reports, 2023 Murburn concept is a novel perspective for understanding cellular function, deeming cells as simple chemical engines (SCE) that are powered by redox reactions initiated by effective charge separation (ECS).
Kelath Murali Manoj
doaj +1 more source