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Superoxide dismutase ameliorates oxidative stress and regulates liver transcriptomics to provide therapeutic benefits in hepatic inflammation [PDF]

open access: yesPeerJ, 2023
Background Oxidative stress refers to the imbalance between oxidants and antioxidants in organisms and often induces hepatic inflammation. Supplementing exogenous superoxide dismutase is an effective way to alleviate oxidative stress; however, the ...
Longyan Chen   +7 more
doaj   +2 more sources

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase [PDF]

open access: yes, 2012
Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O2 and H2O2. SOD also reacts with H2O2, leading to the formation of a strong
Luis Eduardo Soares Netto   +4 more
core   +10 more sources

Neonatal Extracellular Superoxide Dismutase Knockout Mice Increase Total Superoxide Dismutase Activity and VEGF Expression after Chronic Hyperoxia

open access: yesAntioxidants, 2021
Bronchopulmonary dysplasia (BPD) is a common lung disease affecting premature infants that develops after exposure to supplemental oxygen and reactive oxygen intermediates.
Maxwell Mathias   +3 more
doaj   +1 more source

The effect of aerobic stress on superoxide dismutase and glutathione and relations with Calcium blood in football players [PDF]

open access: yesمجلة الرافدين للعلوم الرياضية, 2022
The Research aim: -      The effect of Aerobic stress in superoxide dismutase and glutathione in football players in blood serum. -      To identify on relation between superoxide dismutase and glutathione with calcium in blood serum after Aerobic ...
Bestoon Ahmad
doaj   +1 more source

Enterocyte superoxide dismutase 2 deletion drives obesity

open access: yesiScience, 2022
Summary: Compelling evidence support an involvement of oxidative stress and intestinal inflammation as early events in the predisposition and development of obesity and its related comorbidities.
Oihane Garcia-Irigoyen   +18 more
doaj   +1 more source

Amide-π interactions in active centers of superoxide dismutase [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
In this work, the influence of amide–π interactions on stability and properties of superoxide dismutase (SOD) active centres was analysed. In the data set of 43 proteins, 5017 amide–π interactions were observed, and every active centre formed averagely ...
Stojanović Srđan Đ.   +2 more
doaj   +1 more source

Superoxide dismutase

open access: yesParasitology Today, 1994
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
Dietmar Schomburg, Dörte Stephan
  +6 more sources

Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury

open access: yesAntioxidants, 2021
Cisplatin is a chemotherapy agent commonly used to treat a wide variety of cancers. Despite the potential for both severe acute and chronic side effects, it remains a preferred therapeutic option for many malignancies due to its potent anti-tumor ...
Kranti A. Mapuskar   +11 more
doaj   +1 more source

Methylglyoxal interaction with superoxide dismutase 1

open access: yesRedox Biology, 2020
Methylglyoxal (MG) is a highly reactive aldehyde spontaneously formed in human cells mainly as a by-product of glycolysis. Such endogenous metabolite reacts with proteins, nucleotides and lipids forming advanced glycation end-products (AGEs). MG binds to
Panagis Polykretis   +3 more
doaj   +1 more source

The landscape of cognitive impairment in superoxide dismutase 1-amyotrophic lateral sclerosis

open access: yesNeural Regeneration Research, 2023
Although mutations in the superoxide dismutase 1 gene account for only a minority of total amyotrophic lateral sclerosis cases, the discovery of this gene has been crucial for amyotrophic lateral sclerosis research. Since the identification of superoxide
Ilaria Martinelli   +6 more
doaj   +1 more source

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