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Strand-Swapped SH3 Domain Dimer with Superoxide Dismutase Activity. [PDF]
Häge FR+8 more
europepmc +2 more sources
Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase [PDF]
Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O2 and H2O2. SOD also reacts with H2O2, leading to the formation of a strong
Luis Eduardo Soares Netto+4 more
core +7 more sources
Amide-π interactions in active centers of superoxide dismutase [PDF]
In this work, the influence of amide–π interactions on stability and properties of superoxide dismutase (SOD) active centres was analysed. In the data set of 43 proteins, 5017 amide–π interactions were observed, and every active centre formed averagely ...
Stojanović Srđan Đ.+2 more
doaj +1 more source
Superoxide dismutase nanozymes: an emerging star for anti-oxidation.
Superoxide dismutases (SODs) are a group of metalloenzymes that catalyze the dismutation of superoxide radicals (O2˙-) into hydrogen peroxide (H2O2) and oxygen (O2). As the first line of defense against reactive oxygen species (ROS)-mediated damage, SODs
Hanqing Zhao+3 more
semanticscholar +1 more source
Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury
Cisplatin is a chemotherapy agent commonly used to treat a wide variety of cancers. Despite the potential for both severe acute and chronic side effects, it remains a preferred therapeutic option for many malignancies due to its potent anti-tumor ...
Kranti A. Mapuskar+11 more
doaj +1 more source
Superoxide Dismutase Administration: A Review of Proposed Human Uses
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant defense against oxidative stress in the body. SOD supplementation may therefore trigger the endogenous antioxidant machinery for the neutralization of free-radical ...
A. C. Rosa+4 more
semanticscholar +1 more source
The landscape of cognitive impairment in superoxide dismutase 1-amyotrophic lateral sclerosis
Although mutations in the superoxide dismutase 1 gene account for only a minority of total amyotrophic lateral sclerosis cases, the discovery of this gene has been crucial for amyotrophic lateral sclerosis research. Since the identification of superoxide
Ilaria Martinelli+6 more
doaj +1 more source
The crystal structure of superoxide dismutase from Plasmodium falciparum [PDF]
Background: Superoxide dismutases (SODs) are important enzymes in defence against oxidative stress. In Plasmodium falciparum, they may be expected to have special significance since part of the parasite life cycle is spent in red blood cells where the ...
Boucher, Ian W.+6 more
core +3 more sources
Abstract Fresh chicken liver contains two types of superoxide dismutase, one of which is localized in the mitochondria while the other is found in the cytosol. The mitochondrial superoxide dismutase was inactivated by treatment with mixtures of chloroform and ethanol whereas the cytosol superoxide dismutase was not. The cytosol superoxide dismutase was
Richard A. Weisiger, Irwin Fridovich
openaire +2 more sources
The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6. The rate of autoxidation increases with increasing pH.
S. Marklund, Gudrun Marklund
semanticscholar +1 more source