Results 11 to 20 of about 248,641 (339)

Succinate Dehydrogenase, Succinate, and Superoxides: A Genetic, Epigenetic, Metabolic, Environmental Explosive Crossroad

open access: yesBiomedicines, 2022
Research focused on succinate dehydrogenase (SDH) and its substrate, succinate, culminated in the 1950s accompanying the rapid development of research dedicated to bioenergetics and intermediary metabolism.
Paule Bénit   +6 more
doaj   +2 more sources

Unprecedented Nonphotomediated Hole (h+) Oxidation System Constructed from Defective Carbon Nanotubes and Superoxides

open access: yesACS Central Science, 2021
Holes (h+) on heterogeneous photocatalysts could act as important oxidative species or precursors for reactive oxygen species (ROS). However, due to the ultrafast recombination of photoinduced electrons and holes, a majority of carriers are consumed ...
Junhui Wang   +6 more
doaj   +2 more sources

Stability of Proton Superoxide and its Superionic Transition Under High Pressure [PDF]

open access: yesAdvanced Science
Under extreme conditions, condensed matters are subject to undergo a phase transition and there have been many attempts to find another form of hydroxide stabilized over H2O.
Zifan Wang, Wenge Yang, Duck Young Kim
doaj   +2 more sources

Mitochondrial blood‐based biomarker is related to cardiorespiratory fitness and aging in a sex‐dependent manner [PDF]

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION A sedentary lifestyle increases the risk for Alzheimer's disease (AD), whereas exercise has been shown to benefit brain health. Physiological factors, such as female sex, are linked to lower cardiorespiratory fitness and can increase the ...
Riley E. Kemna   +9 more
doaj   +2 more sources

G-Quadruplexes Abet Neuronal Burnout in ALS and FTD [PDF]

open access: yesAntioxidants
Expansion of d(GGGGC)n repeat in the C9ORF72 gene is causal for Amyotrophic Lateral Sclerosis (ALS) and Frontal Temporal Dementia (FTD). Proposed mechanisms include Repeat-Associated Non-AUG translation or the formation of G-quadruplexes (GQ) that ...
Alan Herbert
doaj   +2 more sources

Red LED Light Irradiation Increases the Resistance Against Environmental Stress of Frozen Bovine Sperm Thawed in Suboptimal Conditions [PDF]

open access: yesAnimals
This work sought to test the positive effect of red LED light on frozen bovine sperm resistance to thawing in suboptimal conditions. Moreover, a preliminary study explores whether this improvement could have any repercussions on in vivo fertilizing ...
Olga Blanco-Prieto   +13 more
doaj   +2 more sources

Role of reactive oxygen species in ultraviolet-induced photodamage of the skin

open access: yesCell Division
Reactive oxygen species (ROS), such as superoxides (O2 •−) and hydroxyl groups (OH·), are short-lived molecules containing unpaired electrons. Intracellular ROS are believed to be mainly produced by the mitochondria and NADPH oxidase (NOX) and can be ...
Min Wei, Xin He, Na Liu, Hui Deng
doaj   +2 more sources

Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans

open access: yeseLife, 2018
Mitochondrial dysfunction and subsequent metabolic deregulation is observed in neurodegenerative diseases and aging. Mutations in the presenilin (PSEN) encoding genes (PSEN1 and PSEN2) cause most cases of familial Alzheimer’s disease (AD); however, the ...
Shaarika Sarasija   +5 more
doaj   +2 more sources

Cannabidiol and Beta-Caryophyllene Combination Attenuates Diabetic Neuropathy by Inhibiting NLRP3 Inflammasome/NFκB through the AMPK/sirT3/Nrf2 Axis [PDF]

open access: yesBiomedicines
Background: In this study, we investigated in detail the role of cannabidiol (CBD), beta-caryophyllene (BC), or their combinations in diabetic peripheral neuropathy (DN).
Islauddin Khan   +5 more
doaj   +2 more sources

Superoxide Radical Formed on the TiO2 Surface Produced from Ti(OiPr)4 Exposed to H2O2/KOH

open access: yesInorganics, 2023
In this study, the superoxide radical O2•− formed by treating Ti(OR)4 (R = iPr, nBu) with H2O2 in the presence of KOH was detected in the EPR spectra. The g-tensor of this radical differs from the typical values reported for a superoxide on various TiO2 ...
Rimma I. Samoilova, Sergei A. Dikanov
doaj   +1 more source

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