Results 191 to 200 of about 9,691 (244)

Cryopreservation of bovine sperm causes single-strand DNA breaks that are localized in the toroidal regions of chromatin. [PDF]

J Anim Sci Biotechnol
Ribas-Maynou J, Muiño R, Tamargo C, Yeste M.   +3 more
europepmc   +1 more source

A rational strategy to optimize photodrugs by Molecular Dynamics simulations for killing drug‐resistant Gram‐negative bacteria

AIChE Journal, EarlyView.
Abstract Antimicrobial resistance has become a major threat to human health, particularly for Gram‐negative bacteria such as Acinetobacter baumannii and Klebsiella pneumoniae. Disruption of membrane integrity is regarded as a promising antimicrobial strategy that does not induce distinct drug resistance, while increasing the internalization of drug ...
Lei Hao, Yeonho Song, Cheng Zhang, Yumei Wang, Haoying Ge, Wen Sun, Jingyun Wang, Jun Soo Kim, Xiaojun Peng, Juyoung Yoon, Haidong Li   +10 more
wiley   +1 more source

The Respiratory Burst of Human Granulocytes Is Mostly Independent of Potassium. [PDF]

Biomolecules
Mahorivska I, Geltinger M, Chaves G, Lobmann S, Jakab M, Helm K, Musset B.   +6 more
europepmc   +1 more source

Feature Selection for Machine Learning‐Driven Accelerated Discovery and Optimization in Emerging Photovoltaics: A Review

Advanced Intelligent Discovery, EarlyView.
Feature selection combined with machine learning and high‐throughput experimentation enables efficient handling of high‐dimensional datasets in emerging photovoltaics. This approach accelerates material discovery, improves process optimization, and strengthens stability prediction, while overcoming challenges in data quality and model scalability to ...
Jiyun Zhang, Jiayi Tan, Qizhen Song, Tian Du, Jens Hauch, Christoph J. Brabec   +5 more
wiley   +1 more source

Unveiling the Renoprotective Mechanisms of Schisandrin B in Ischemia-Reperfusion Injury Through Transcriptomic and Pharmacological Analysis. [PDF]

Drug Des Devel Ther
Xu C, Deng Y, Man J, Wang H, Che T, Ding L, Yang L.   +6 more
europepmc   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Flavonoids in the treatment of <i>Leishmania amazonensis</i>: a review of efficacy and mechanisms. [PDF]

Front Pharmacol
Lessa VL, Drescher G, Gonçalves G, Lopes JCB, Vieira RFDC, Figueiredo FB.   +5 more
europepmc   +1 more source

Increased ROS and Persistent Pro-Inflammatory Responses in a Diabetic Wound Healing Model (db/db): Implications for Delayed Wound Healing. [PDF]

Int J Mol Sci
Elajaili H, Lyttle BD, Lewis CV, Bardill JR, Dee N, Seal S, Nozik ES, Liechty KW, Zgheib C.   +8 more
europepmc   +1 more source

Sensight enables quantitative multivariate engineering of high-performance chemical imaging tools. [PDF]

Nat Commun
Wen C, Jiang Y, Shen T, Jiang X, Fan S, Yang T, Liu X, Luo Q, Li X.   +8 more
europepmc   +1 more source

Bimetallic Cu/Zn Single-Atom Nanozyme with Superoxide Dismutase-Like Activity. [PDF]

Small
Hamed EM, Fung FM, Li SFY.
europepmc   +1 more source