Results 201 to 210 of about 9,801 (264)

Oxidative Stress in Keratoconus Is Evident in Tear Fluid and Stromal Cells and Alleviated in Cell Culture by Sulforaphane. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Koduri MA   +13 more
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Superoxide, Superoxide Dismutase and the Respiratory Burst

Veterinary Clinical Pathology, 1983
SummaryPhagocytes undergo a sharp burst of oxygen consumption when engulfing bacteria. This oxygen is enzymatically reduced to toxic metabolites which are essential to the bactericidal action of the cell. Oxygen metabolites formed in this burst as well as other intermediates formed in biological reduction reactions do not selectively reserve their ...
H S, Bender, W R, Chickering
openaire   +2 more sources

The Reaction of no With Superoxide

Free Radical Research Communications, 1993
The rate constant for the reaction of NO with .O2- was determined to be (6.7 +/- 0.9) x 10(9) l mol-1 s-1, considerably higher than previously reported. Rate measurements were made from pH 5.6 to 12.5 both by monitoring the loss of .O2- and the formation of the product -OONO.
R E, Huie, S, Padmaja
openaire   +2 more sources

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

Annual Review of Biochemistry, 1972
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
openaire   +2 more sources

Theoretical Studies of Manganese and Iron Superoxide Dismutases:  Superoxide Binding and Superoxide Oxidation

The Journal of Physical Chemistry B, 2005
Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu   +2 more
openaire   +2 more sources

Superoxide Dismutase Mimetics

Pulmonary Pharmacology & Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D   +3 more
openaire   +3 more sources

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