Results 191 to 200 of about 9,801 (264)

Ecotoxicological Evaluation of Organic Sunscreens Used Worldwide, Alone and in Mixture, on Terrestrial Plants. [PDF]

Environ Toxicol
Santo DE, de Almeida EA, Dusman E, Downs AC, da Silva Gonzalez R, Junior OV, Peron AP.   +6 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Electron paramagnetic resonance spectroscopy for analysis of free radicals in zebrafish. [PDF]

PLoS One
Sabetghadam Moghadam M, Wiens E, Gauvrit S, Sammynaiken R, Collins MM.   +4 more
europepmc   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Cellular responses to prolonged non-thermal plasma exposure in Schizosaccharomyces pombe. [PDF]

Appl Microbiol Biotechnol
Petkova M, Durcanyova S, Kutka M, Kyzekova I, Gaplovska-Kysela K, Soltys K, Kyzek S, Medvecka V, Sevcovicova A.   +8 more
europepmc   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy. [PDF]

Invest Ophthalmol Vis Sci
Lessieur EM, Saadane A, Du Y, Kiser J, Oum A, Bollinger ZR, Lee CA, Tang J, Kern TS.   +8 more
europepmc   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Regulation of Ferroptosis Sensitivity in Hepatocellular Carcinoma Cells by Lysosomal Ion Channels TPC2 and TRPML1. [PDF]

Antioxidants (Basel)
Geisslinger F, Gell V, Witt F, Jaślan D, Grimm C, Koeberle A, Bartel K.   +6 more
europepmc   +1 more source

Baicalin Prevents Chronic β-AR Agonist-Induced Heart Failure via Preventing Oxidative Stress and Overactivation of the NADPH Oxidase NOX2. [PDF]

J Cell Mol Med
Ge Y, Ma E, Guo X, Wang Q, Zhu W, Ren DN, Wo D.   +6 more
europepmc   +1 more source