Results 31 to 40 of about 49,276 (355)

Arginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery

open access: yesJournal of Oral Microbiology
Background Gingipains are important virulence factors present in Porphyromonas gingivalis. Arginine-specific gingipains (RgpA and RgpB) are critically associated with increased proteolytic activity and immune system dysfunction, including neutrophilic ...
Vanessa Tubero Euzebio Alves   +6 more
doaj   +1 more source

Nitrate Increases Aluminum Toxicity and Accumulation in Root of Wheat

open access: yesAgriculture, 2022
Aluminum (Al) toxicity inhibits root growth, while nitrogen is an essential nutrient for plant growth and development. To explore the effects of nitrate (N) on Al toxicity and accumulation in root of wheat, two wheat genotypes, Shengxuan 6 hao (SX6, Al ...
Yan Ma   +3 more
doaj   +1 more source

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. [PDF]

open access: yes, 2017
Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation ...
Chwa, Marilyn   +6 more
core   +1 more source

Deactivation of the JNK Pathway by GSTP1 Is Essential to Maintain Sperm Functionality

open access: yesFrontiers in Cell and Developmental Biology, 2021
Fifty percent of male subfertility diagnosis is idiopathic and is usually associated with genetic abnormalities or protein dysfunction, which are not detectable through the conventional spermiogram.
Marc Llavanera   +13 more
doaj   +1 more source

Cellular Antioxidant Effects and Bioavailability of Food Supplements Rich in Hydroxytyrosol

open access: yesApplied Sciences, 2021
The present study evaluates the effect of olive (Olea europaea L.) vegetation water on human cells regarding its antioxidant properties and radical scavenger bioactivities.
Cecilia Bender   +2 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Oxygen plasmas used to synthesize superoxides [PDF]

open access: yes, 1972
Production of alkali metal superoxides by interaction of molecular oxygen with alkali metals or their salts is discussed. Diagram of reactor to show components and operating principles is provided.
Hollahan, J. R., Wydeven, T.
core   +1 more source

Role of Protons in Superoxide Reduction by a Superoxide Reductase Analogue [PDF]

open access: yesInorganic Chemistry, 2005
Superoxide reduction by thiolate-ligated [FeII(SMe2N4(tren))]+ (1) involves two proton-dependent steps and a single peroxide intermediate, [FeIII(SMe2N4(tren))(OOH)]+ (2). An external proton donor is required, ruling out mechanisms involving H+ or H-atom abstraction from the ligand N-H.
Julie A. Kovacs, Roslyn M. Theisen
openaire   +3 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

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