Rubidium superoxide: a p-electron Mott insulator [PDF]
Rubidium superoxide, RbO_2, is a rare example of a solid with partially-filled electronic p states, which allows to study the interplay of spin and orbital order and other effects of strong electronic correlations in a material that is quite different ...
Claude Ederer +4 more
core +2 more sources
Arginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery
Background Gingipains are important virulence factors present in Porphyromonas gingivalis. Arginine-specific gingipains (RgpA and RgpB) are critically associated with increased proteolytic activity and immune system dysfunction, including neutrophilic ...
Vanessa Tubero Euzebio Alves +6 more
doaj +1 more source
Nitrate Increases Aluminum Toxicity and Accumulation in Root of Wheat
Aluminum (Al) toxicity inhibits root growth, while nitrogen is an essential nutrient for plant growth and development. To explore the effects of nitrate (N) on Al toxicity and accumulation in root of wheat, two wheat genotypes, Shengxuan 6 hao (SX6, Al ...
Yan Ma +3 more
doaj +1 more source
Extracellular superoxide dismutase VdSOD5 is required for virulence in Verticillium dahliae
Plants produce reactive oxygen species (ROS) to defend pathogens. To counteract this attack, certain pathogens express superoxide dismutases (SODs) to scavenge host-derived ROS.
Li TIAN +7 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek +5 more
core +1 more source
Mott physics in $2p$ electron dioxygenyl magnet : O$_{2}$$M$F$_{6}$ ($M$=Sb, Pt)
We have investigated electronic structures and magnetic properties of O$_{2}$$M$F$_{6}$ ($M$=Sb, Pt), which are composed of two building blocks of strongly correlated electrons: O$_{2}^{+}$ dioxygenyls and $M$F$_{6}^{-}$ octahedra, by employing the first-
Kim, Minjae, Min, B. I.
core +1 more source
Improved description of metal oxide stability:Beyond the random phase approximation with renormalized kernels [PDF]
The renormalized adiabatic PBE (rAPBE) method has recently been shown to comprise a significant improvement over the random phase approximation (RPA) for total energy calculations of simple solids and molecules. Here we consider the formation energies of
Bligaard, Thomas +3 more
core +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Deactivation of the JNK Pathway by GSTP1 Is Essential to Maintain Sperm Functionality
Fifty percent of male subfertility diagnosis is idiopathic and is usually associated with genetic abnormalities or protein dysfunction, which are not detectable through the conventional spermiogram.
Marc Llavanera +13 more
doaj +1 more source

