Results 51 to 60 of about 1,809,313 (357)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Dynamic MAML with Efficient Multi-Scale Attention for Cross-Load Few-Shot Bearing Fault Diagnosis

Entropy
Accurate bearing fault diagnosis under various operational conditions presents significant challenges, mainly due to the limited availability of labeled data and the domain mismatches across different operating environments.
Qinglei Zhang, Yifan Zhang, Jiyun Qin, Jianguo Duan, Ying Zhou   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Research on Classification and Identification of Crack Faults in Steam Turbine Blades Based on Supervised Contrastive Learning

Entropy
Steam turbine blades may crack, break, or suffer other failures due to high temperatures, high pressures, and high-speed rotation, which seriously threatens the safety and reliability of the equipment.
Qinglei Zhang, Laifeng Tang, Jiyun Qin, Jianguo Duan, Ying Zhou   +4 more
doaj   +1 more source

Investigating stock-outs in Johannesburg’s warehouse retail liquor sector

Journal of Transport and Supply Chain Management, 2017
Purpose: The aim of this exploratory study was to investigate how management practices and processes contribute to stock-outs in the warehouse retail liquor sector in Johannesburg.
Amit Govind, Rose Luke, Noleen Pisa
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Measuring Circular Supply Chain Risk: A Bayesian Network Methodology [PDF]

, 2021
Madhukar Chhimwal, Saurabh Agrawal, Girish Kumar   +2 more
openalex   +1 more source

Sustainable Supply Chains: Introduction

, 2016
As firms become progressively more tightly coupled in global supply chains, rather than being large vertically integrated monoliths, risks and opportunities associated with activities, upstream or downstream, will increasingly impinge upon their own well-being.
Bouchery, Yann, Corbett, Charles J, Fransoo, Jan C, Tan, Tarkan   +3 more
openaire   +2 more sources

Designing Enterprise Resources Planning Application for Integrating Main Activities in a Simulator Model of SCM Network Distribution [PDF]

, 2009
Collaborative supply chain is a specific topic in supply chain management and studied by industrial engineering students in supply chain management course.
Hakim, Inaki Maulida, Hisjam, Muh., Sutopo, Wahyudi, Yuniaristanto,   +3 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source