Results 51 to 60 of about 1,832,123 (358)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Dynamic MAML with Efficient Multi-Scale Attention for Cross-Load Few-Shot Bearing Fault Diagnosis

Entropy
Accurate bearing fault diagnosis under various operational conditions presents significant challenges, mainly due to the limited availability of labeled data and the domain mismatches across different operating environments.
Qinglei Zhang, Yifan Zhang, Jiyun Qin, Jianguo Duan, Ying Zhou   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Research on Classification and Identification of Crack Faults in Steam Turbine Blades Based on Supervised Contrastive Learning

Entropy
Steam turbine blades may crack, break, or suffer other failures due to high temperatures, high pressures, and high-speed rotation, which seriously threatens the safety and reliability of the equipment.
Qinglei Zhang, Laifeng Tang, Jiyun Qin, Jianguo Duan, Ying Zhou   +4 more
doaj   +1 more source

Investigating stock-outs in Johannesburg’s warehouse retail liquor sector

Journal of Transport and Supply Chain Management, 2017
Purpose: The aim of this exploratory study was to investigate how management practices and processes contribute to stock-outs in the warehouse retail liquor sector in Johannesburg.
Amit Govind, Rose Luke, Noleen Pisa
doaj   +1 more source

Bridging sustainability knowledge management and supply chain learning: evidence through buyer selection [PDF]

, 2023
Minelle E. Silva, Michele Morais Oliveira Pereira, Albachiara Boffelli   +2 more
openalex   +1 more source

Designing Enterprise Resources Planning Application for Integrating Main Activities in a Simulator Model of SCM Network Distribution [PDF]

, 2009
Collaborative supply chain is a specific topic in supply chain management and studied by industrial engineering students in supply chain management course.
Hakim, Inaki Maulida, Hisjam, Muh., Sutopo, Wahyudi, Yuniaristanto,   +3 more
core  

Rethinking fuelwood: people, policy and the anatomy of a charcoal supply chain in a decentralizing Peru [PDF]

, 2018
In Peru, as in many developing countries, charcoal is an important source of fuel. We examine the commercial charcoal commodity chain from its production in Ucayali, in the Peruvian Amazon, to its sale in the national market.
Bennett, Aoife, Cronkleton, Peter, Malhi, Yadvinder, Menton, Mary   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source