Results 81 to 90 of about 1,809,313 (357)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Study on the Multi-Equipment Integrated Scheduling Problem of a U-Shaped Automated Container Terminal Based on Graph Neural Network and Deep Reinforcement Learning

Journal of Marine Science and Engineering
Intelligent Guided Vehicles (IGVs) in U-shaped automated container terminals (ACTs) have longer travel paths than those in conventional vertical layout ACTs, and their interactions with double trolley quay cranes (DTQCs) and double cantilever rail cranes
Qinglei Zhang, Yi Zhu, Jiyun Qin, Jianguo Duan, Ying Zhou, Huaixia Shi, Liang Nie   +6 more
doaj   +1 more source

Evolution of Supply Chain Collaboration: Implications for the Role of Knowledge [PDF]

, 2014
Increasingly, research across many disciplines has recognized the shortcomings of the traditional “integration prescription” for inter-organizational knowledge management.
Farris, M. Theodore, Gravier, Michael
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

FedEx Case Study: Links in the Chain [PDF]

Supply chain management improves competition by controlling costs and shortening product delivery cycles.supply chain, global supply chain, FedEx, supply chain management, Tennessee ...
Scott Gardner
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The structure of cross-ventilation flow in an isolated cylindrical building: Numerical study

Energy and Built Environment
Cross-ventilation serves as an efficient means to expel pollutants and heat from buildings, requiring no energy consumption due to variations in wind pressure. The structure of the cross-ventilation flow significantly influences ventilation effectiveness.
Puxian Ding, Di Fan, Ye Feng, Shiming Liu, Xiaoqing Zhou   +4 more
doaj   +1 more source

Sustainability of food supply chains – mapping food waste and by-product synergies [PDF]

, 2015
Purpose: This conceptual paper introduces the theoretical and methodological basis of an analytical framework conceived with the purpose of bringing industrial ecology perspectives into the core of the underlying disciplines supporting studies concerned ...
Batista, Luciano, Fouto, Nuno, Saes, Sylvia   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Taxonomy of digital signage message execution and media placement considerations [PDF]

The Retail and Marketing Review, 2020
Digital signage is a commercial promising field in marketing. Yet, it is a little researched topic, with an incomplete understanding of the factors to consider when planning digital signage message executions or media placements.
E M Xaba, AT Roux, GAP Drotsky
doaj