Results 61 to 70 of about 3,251,666 (288)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Job placement strategies used by community rehabilitation programs and client employment outcomesa study of three diagnostic categories [PDF]
, 2002 Plan BThis descriptive study surveys the placement methods used by Community Rehabilitation Programs in Minnesota and Wisconsin to place adults with Mental Retardation, Mental Illness, and Traumatic Brain Injury into integrated employment.
Hughes, Paul
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The World of Public Employment Services [PDF]
, 2016 Public employment services are challenged by expectations of growth, changing conditions in the labor market, and institutional contexts. An important step to meet those challenges, and to better support the strengthening and modernization of public ...
Inter-American Development Bank
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Increasing employment rates for Indigenous people with a disability [PDF]
, 2014 Introduction: The purpose of this resource sheet is to assess and summarise evidence on the effectiveness of programs relevant to increasing employment rates for Aboriginal and Torres Strait Islander people with a disability.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Supported employment : persons with learning difficulties in Malaysia [PDF]
Many studies in the minority world have emphasized the potentially positive influences of supported as opposed to sheltered employment on the inclusion of persons with disabilities, including learning difficulties, into the mainstream economy and ...
Wan Abdullah, Wan Arnidawati
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Supported Employment for arbeidssøkere med bistandsbehov: en systematisk oversikt [PDF]
, 2017 Background Eight billion kroner from the Norwegian state budget is used on employment interventions every year. These interventions primarily target and assist individuals with reduced work capacity (in need of assistance).
Berg, Rigmor +2 more
core +1 more source