Results 71 to 80 of about 12,024,358 (339)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Does Individual Placement and Support satisfy the users` needs?
Frontiers in Public Health, 2015 This study aims to investigate clients’ satisfaction with Individual Placement and Support (IPS) at the University Hospital for Psychiatry Zurich (PUK).
Sandra eViering +8 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Employment Incentives to Support “Employment First” [PDF]
Global Journal of Intellectual & Developmental Disabilities, 2018 As the nation moves to implement the “Employment First†initiative for citizens who have intellectual disability, one must question whether there are sufficient numbers of community based jobs to support the needs of individuals who have intellectual disability.
openaire +1 more source
Supported Employment: A Best Practice for People with Psychiatric Disabilities [PDF]
, 2006 Over the past several decades, research from a variety of fields has presented powerful evidence of the importance of employment to people with psychiatric disabilities.
Cook, Judith A., O\u27Day, Bonnie
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Promoting the Readiness of Minors in Supplemental Security Income (PROMISE) [CFDA 84.418P] [PDF]
, 2013 Over the past two decades, New York State (NYS) has been actively and collaboratively engaged in systems change across three primary domains: 1) to develop a comprehensive employment system to reduce barriers to work and improve employment outcomes of ...
Employment and Disability Institute +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
International Journal of Public HealthObjectiveThis randomised controlled trial examined whether individuals with severe mental disorders (SMD) in a high-unemployment context benefit in mental health, functional and vocational outcomes when receiving the Individual Placement and Support (IPS)
Francisco Rodríguez Pulido +5 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source