Results 91 to 100 of about 314,869 (336)

SUPPORTED EMPLOYMENT – THE WAY TO INTEGRATION AND INDEPENDENCE FOR PEOPLE IN A HOMELESSNESS CRISIS

Humanities and Social Sciences
The supported employment model for homeless people is based on a holistic approach that combines professional, housing, health, and social support.
Agnieszka MIKLEWSKA
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Employment of persons with disabilities in the open labour market: A scoping review

African Journal of Disability
Background: Persons with disabilities are often disproportionately placed in part-time roles, confined to low occupational levels and face a heightened risk of job loss perpetuating a cycle of underemployment, leaving many to earn below the official ...
Themba M. Ximba, Hester M. van Biljon, Fasloen Adams, Lana van Niekerk   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Supported Employment in Britain [PDF]

, 1997
This paper describes supported employment, its growth as an alternative to traditional day services and research which indicates potentially beneficial outcomes in the areas of increased employee income, social integration, satisfaction, engagement in ...
Stephen Beyer, Mark Kilsby
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Employment Incentives to Support “Employment First” [PDF]

Global Journal of Intellectual & Developmental Disabilities, 2018
As the nation moves to implement the “Employment First†initiative for citizens who have intellectual disability, one must question whether there are sufficient numbers of community based jobs to support the needs of individuals who have intellectual disability.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Analysis of factors influencing satisfaction with vocational rehabilitation services for young persons with disabilities in Sweden

Frontiers in Rehabilitation Sciences
PurposeThe purpose of this study is to identify what factors influence user satisfaction with vocational rehabilitation services among service users in a Swedish context.MethodsIn a randomized control trial, ordinal logistic regression was applied to a ...
Johanna Gustafsson, Johanna Gustafsson, Johanna Gustafsson, Ingrid Witte, Ingrid Witte, Ingrid Witte   +5 more
doaj   +1 more source

Enhancing Autonomy through the Occupational Engagement of Adults with Intellectual Disabilities: Supported Employment Model Applied by the Polish Association for Persons with Intellectual Disabilities (Branch in Zgierz)

Przeglad Socjologii Jakosciowej, 2019
Reflections presented in this paper reverberate with the current social discourse based on respect for human rights, with heavy emphasis put on the active policy of employment of persons with disabilities.
Grażyna Mikołajczyk-Lerman, Małgorzata Potoczna   +1 more
doaj   +1 more source