Results 111 to 120 of about 314,869 (336)
Merging Evidence-Based Psychosocial Interventions in Schizophrenia
Behavioral Sciences, 2014 Psychosocial interventions are an essential part of the treatment for people with severe mental illness such as schizophrenia. The criteria regarding what makes an intervention “evidence-based” along with a current list of evidence-based interventions ...
Tania Lecomte +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2015 Title from PDF caption (viewed on April 17, 2019)."Xiao ji tuan zhi chi jiu ye ji hui zhi ji tuan(shao yu 8 ren)zuo wei xing dong xiao zu huo gong zuo zu kai zhan de fu wu he huo dong."This archived document is maintained by the State Library of Oregon ...
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Diversifying the supported employment workforce : values, critical analysis abilities, and self-efficacy ratings of business and social service students [PDF]
, 2005 Supported employment has been shown to be an effective way to contribute to the community reintegration of persons with disabilities. Traditionally, the hiring practice for supported employment staffs has focused on individuals with social service ...
Galka, Steven W.
core
Dagtilbud, en vei til deltakelse i ordinært arbeidsliv for personer med utviklingshemming?
Nordisk VälfärdsforskningArbeidsinkludering og arbeid for alle er sentrale politiske mål i Norge. Det er få personer med utviklingshemming som deltar i ordinært arbeidsliv. Personer med utviklingshemming har i hovedsak varig tilrettelagt arbeid (VTA) på skjermet arbeidsplass ...
Linda Barøy +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source