Results 111 to 120 of about 3,251,666 (288)
The Role of Shared Resilience in Building Employment Pathways with People with a Disability
DisabilitiesFor workers living with a disability, pathways to sustainable employment in the open labour market are inhibited by barriers operating at different structural and societal levels.
Perri Campbell +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Iterations of work inclusion beyond the standard service
Journal of Comparative Social WorkEmployment services are repeatedly criticised for building barriers to service user participation and decent employment due to combinations of conditionality, bureaucratic logics, high caseloads and scarce resources.
Kjetil G. Lundberg +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Supported employment in Norway [PDF]
, 2004 This report presents research on the Norwegian labour market measure Arbeid med bistand (AB). AB is a national mainstream supported employment programme, which provides support aimed at the inclusion of vocationally disabled job seekers in the ordinary ...
Spjelkavik, Øystein +2 more
core +1 more source
Supported employment interventions for workplace mental health of persons with mental disabilities in low-to-middle income countries: A scoping review. [PDF]
PLoS One, 2023 Mavindidze E, Nhunzvi C, Van Niekerk L.
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source