Results 221 to 230 of about 2,656,520 (276)
Angewandte Chemie, EarlyView.We report a super‐resolution strategy that maps cholesterol‐rich membrane domains in whole, intact cells with an effective spatial resolution of ∼40 nm by combining expansion microscopy with a perfringolysin O domain 4 probe. This approach enables direct visualization of the spatial association between CD20 and CD38 complexes and cholesterol‐rich ...
Gang Wen +9 more
wiley +2 more sources
Advanced Intelligent Discovery, EarlyView.AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula +10 more
wiley +1 more source
Backbone Steric Constraints Underlie High Passive Membrane Permeability of N‐Alkyl Peptides
Angewandte Chemie, EarlyView.Beyond amide hydrogen removal, steric constraints encoded in N/Cα‐dually substituted backbones are uncovered as a key determinant of passive membrane permeability in N‐alkyl peptides. These constraints restrict conformational freedom and sterically limit backbone hydration during membrane permeation.
Ayumi Inayoshi +8 more
wiley +2 more sources
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Light‐Enhanced Chloride Transport by Thiourea‐Appended Molecular Motor
Angewandte Chemie, EarlyView.A molecular motor functionalized with a thiourea anion‐binding motif mediates transmembrane chloride transport. Light irradiation enhances transport efficiency by populating a more active metastable isomer, which slowly equilibrates to the initial stable isomer.
Abhishek Mondal, Sander J. Wezenberg
wiley +2 more sources
Angewandte Chemie, EarlyView.This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen +3 more
wiley +2 more sources
Polyproline: A Synthetic Polypeptide With Unique Properties
Angewandte Chemie, EarlyView.Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec +3 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini +13 more
wiley +2 more sources