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Dynamic and mechanical properties of supported lipid bilayers
The Journal of Chemical Physics, 2016Supported lipid bilayers (SLBs) offer an excellent model system for investigating the physico-chemical properties of the cell membrane. In this work, dynamic and mechanical properties of SLBs are explored by dissipative particle dynamics simulations for lipids with different architectures (chain length, kink, and asymmetry associated with lipid tails).
Hsing-Lun Wu +2 more
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Cationic supported lipid bilayers for antigen presentation
International Journal of Pharmaceutics, 2007Polystyrene sulfate (PSS) particles (301 nm mean diameter) were covered with single cationic dioctadecyldimethylammonium bromide (DDA) bilayers and used for antigen adsorption and presentation. The antigen was a mixture of purified 18/14 Taenia crassiceps proteins (18/14-Tcra).
N, Lincopan +3 more
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Micropatterning Fluid Lipid Bilayers on Solid Supports
Science, 1997Lithographically patterned grids of photoresist, aluminum oxide, or gold on oxidized silicon substrates were used to partition supported lipid bilayers into micrometer-scale arrays of isolated fluid membrane corrals. Fluorescently labeled lipids were observed to diffuse freely within each membrane corral but were confined by the micropatterned barriers.
J T, Groves, N, Ulman, S G, Boxer
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Solvent-assisted preparation of supported lipid bilayers
Nature Protocols, 2019The supported lipid bilayer (SLB) platform is a popular cell membrane mimic that is utilized in the chemical, biological, materials science, and medical fields. To date, SLB preparation has proven challenging because of the need for specialized fabrication equipment, domain-specific knowledge about topics relevant to lipid self-assembly, and extensive ...
Abdul Rahim Ferhan +7 more
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Graphene-Templated Supported Lipid Bilayer Nanochannels
Nano Letters, 2016The use of patterned substrates to impose geometrical restriction on the lateral mobility of molecules in supported lipid membranes has found widespread utility in studies of cell membranes. Here, we template-pattern supported lipid membranes with nanopatterned graphene.
Wan, Li +3 more
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Modification of a Supported Lipid Bilayer by Polyelectrolyte Adsorption
Langmuir, 2004Addition of a weak polyelectrolyte, poly(methacrylic acid) (PMA), to a supported phospholipid bilayer made from 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) depresses the melting temperature and alters the morphology of the bilayer in the gel phase.
Feng, ZV, Granick, S, Gewirth, AA
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Supported Lipid Bilayers with Phosphatidylethanolamine as the Major Component
Langmuir, 2017Phosphatidylethanolamine (PE) is notoriously difficult to incorporate into model membrane systems, such as fluid supported lipid bilayers (SLBs), at high concentrations because of its intrinsic negative curvature. Using fluorescence-based techniques, we demonstrate that having fewer sites of unsaturation in the lipid tails leads to high-quality SLBs ...
Anne M. Sendecki +4 more
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Supported lipid bilayer/carbon nanotube hybrids
Nature Nanotechnology, 2007Carbon nanotube transistors combine molecular-scale dimensions with excellent electronic properties, offering unique opportunities for chemical and biological sensing. Here, we form supported lipid bilayers over single-walled carbon nanotube transistors.
Xinjian, Zhou +3 more
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Supported Lipid Bilayer Formation: Beyond Vesicle Fusion
Langmuir, 2020Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed on solid surfaces and integrated with a wide range of surface-sensitive measurement techniques. SLBs are useful for unravelling details of fundamental membrane biology and biophysics as well as for various medical, biotechnology, and environmental science ...
Joshua A. Jackman, Nam-Joon Cho
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Formation of Lipid Sheaths around Nanoparticle‐Supported Lipid Bilayers
Small, 2012AbstractHigh‐surface‐area nanoparticles often cluster, with unknown effects on their cellular uptake and environmental impact. In the presence of vesicles or cell membranes, lipid adsorption can occur on the nanoparticles, resulting in the formation of supported lipid bilayers (SLBs), which tend to resist cellular uptake.
Ahmed, Selver +4 more
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