Results 241 to 250 of about 749,487 (299)

Current perspectives in sudden unexpected death in epilepsy (SUDEP): epidemiology, research approaches and pathways to prevention. [PDF]

Neurol Res Pract
Mann C, Schubert-Bast S, Rosenow F, Strzelczyk A.   +3 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Gradient Scheme Optimization for PRESS-Localized Edited MRS Using Weighted Pathway Suppression. [PDF]

NMR Biomed
Simegn GL, Shams Z, Murali-Manohar S, Simicic D, Gad A, Song Y, Yedavalli V, Davies-Jenkins CW, Gudmundson AT, Zöllner HJ, Oeltzschner G, Edden RAE.   +11 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

FEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo, Emma Piccoli, Luca Bombardi, Martina Aulitto, Salvatore Fusco   +4 more
wiley   +1 more source

The innate immune IMD pathway is a key regulator of gut microbiome and metabolic homeostasis in the black tiger shrimp (Penaeus monodon). [PDF]

PLoS One
Supungul P, Tang S, Uengwetwanit T, Uawisetwathana U, Angthong P, Arayamethakorn S, Bunphimpapha P, Potibut P, Jangsutthivorawat W, Visudtiphole V, Chaiyapechara S, Rungrassamee W.   +11 more
europepmc   +1 more source

Concomitant COX-1 and COX-2 suppression is not sufficient to induce enteropathy associated with chronic NSAID use. [PDF]

J Clin Invest
Barekat K, Ghosh S, Herrmann C, Keat K, Assenmacher CA, Tanes C, Wilson N, Lordan R, Mrčela A, Rauova L, Sengupta A, Das US, Joshi R, Friedman E, Ritchie MD, Bittinger K, Weljie A, Cadwell K, Bushman FD, Wu GD, FitzGerald GA, Ricciotti E.   +21 more
europepmc   +1 more source

Is It Time to Retire Aldosterone Suppression Testing? [PDF]

Am J Hypertens
Kline GA, Leung AA, Orton D, MacFarlane J, Gurnell M.   +4 more
europepmc   +1 more source