Results 11 to 20 of about 2,809,202 (330)

p53 downregulates the Fanconi anaemia DNA repair pathway

open access: yesNature Communications, 2016
P53 is regarded as the guardian of the genome, however it is known that mice with increased p53 activity display characteristics of dyskeratosis congenita.
Sara Jaber   +4 more
doaj   +1 more source

Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis

open access: yesCell Reports, 2015
Diamond-Blackfan anemia (DBA) is characterized by anemia and cancer susceptibility and is caused by mutations in ribosomal genes, including RPL11. Here, we report that Rpl11-heterozygous mouse embryos are not viable and that Rpl11 homozygous deletion in ...
Lucia Morgado-Palacin   +5 more
doaj   +1 more source

Revisiting interval protection, a.k.a. partial cell suppression, for tabular data [PDF]

open access: yes, 2016
The final publication is available at link.springer.comInterval protection or partial cell suppression was introduced in “M. Fischetti, J.-J. Salazar, Partial cell suppression: A new methodology for statistical disclosure control, Statistics and ...
Castro Pérez, Jordi   +1 more
core   +1 more source

Skill-Related Adaptive Modifications of Gaze Stabilization in Elite and Non-Elite Athletes

open access: yesFrontiers in Sports and Active Living, 2022
The vestibular ocular reflex (VOR) provides gaze stability during head movements by driving eye movements in a direction opposing head motion. Although vestibular-based rehabilitation strategies are available, it is still unclear whether VOR can be ...
Susanne M. van der Veen   +5 more
doaj   +1 more source

Mutant Mice Lacking the p53 C-Terminal Domain Model Telomere Syndromes

open access: yesCell Reports, 2013
Mutations in p53, although frequent in human cancers, have not been implicated in telomere-related syndromes. Here, we show that homozygous mutant mice expressing p53Δ31, a p53 lacking the C-terminal domain, exhibit increased p53 activity and suffer from
Iva Simeonova   +12 more
doaj   +1 more source

Genetic suppression [PDF]

open access: yesWormBook, 2005
Genetic suppression has provided a very powerful tool for analyzing C. elegans. Suppression experiments are facilitated by the ability to handle very large numbers of individuals and to apply powerful selections. Because the animal grows as a self-fertilizing diploid, both dominant and recessive suppressors can be recovered.
openaire   +2 more sources

The mediating role of emotion regulation in the emotional complexity and subjective well-being relationship

open access: yesCurrent Issues in Personality Psychology, 2022
Introduction Emotional complexity involves greater emotional awareness and understanding and associates strongly with adaptive emo-tion regulation. Similarly, regulation of emotion is vital for achieving, restoring, and sustaining subjective well-being ...
Satchit P. Mandal   +3 more
doaj   +1 more source

Immune reactivity features in post-burn dynamics

open access: yesRUDN Journal of Medicine, 2022
Relevance. To date, burn injury remains a complex type of damage to skin tissues. Along with local destructive and dystrophic phenomena, systemic changes in the body are observed.
Alfiya K. Azhikova   +2 more
doaj   +1 more source

Associations Between Emotion Regulation and Life Satisfaction Among University Students From Germany, Hong Kong, and Japan: The Mediating Role of Social Support

open access: yesFrontiers in Psychology, 2021
The social adaptiveness of emotion regulation (ER) may differ across cultures due to different social values for the experience and expression of emotions. Specifically, suppression might disrupt social interactions among Germans, but not among Hong Kong
Fabian Schunk   +3 more
doaj   +1 more source

Sustained suppression [PDF]

open access: yesNature Biomedical Engineering, 2020
Further COVID-19 outbreaks are unavoidable. To detect and suppress them, governments ought to implement a range of public health measures aided by technology.
openaire   +2 more sources

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