Results 11 to 20 of about 526,009 (268)

Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease

mSphere, 2020
The type II secretion system (T2SS) is a conserved transport pathway responsible for the secretion of a range of virulence factors by many pathogens, including Vibrio cholerae. Disruption of the T2SS genes in V.
Chelsea S. Rule, Young-Jun Park, Jaclyn R. Delarosa, Stewart Turley, Wim G. J. Hol, Sarah McColm, Colby Gura, Frank DiMaio, Konstantin V. Korotkov, Maria Sandkvist   +9 more
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P25 and P37 proteins encoded by firespike leafroll-associated virus are viral suppressors of RNA silencing

Frontiers in Microbiology, 2022
Firespike leafroll-associated virus (FLRaV) is a major pathogen associated with firespike (Odontonema tubaeforme) leafroll disease. Phylogenetic analysis showed that FLRaV possesses typical traits of subgroup II members of ampeloviruses, but encodes two ...
Yaqin Wang, Hui Liu, Zhanqi Wang, Yushuang Guo, Tao Hu, Xueping Zhou, Xueping Zhou   +6 more
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Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

Nature Communications, 2017
The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how they
Yavuz Kulaberoglu, Kui Lin, Maxine Holder, Zhongchao Gai, Marta Gomez, Belul Assefa Shifa, Merdiye Mavis, Lily Hoa, Ahmad A. D. Sharif, Celia Lujan, Ewan St. John Smith, Ivana Bjedov, Nicolas Tapon, Geng Wu, Alexander Hergovich   +14 more
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Immune Suppression Mediated by STAT4 Deficiency Promotes Lymphatic Metastasis in HNSCC

Frontiers in Immunology, 2020
Head and neck squamous cell carcinoma (HNSCC) is a prevalent form of cancer with 5-years survival rates around 57%, and metastasis is a leading cause of mortality.
Kelvin Anderson, Nathan Ryan, Greta Volpedo, Greta Volpedo, Sanjay Varikuti, Abhay R. Satoskar, Abhay R. Satoskar, Steve Oghumu   +7 more
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Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans

Frontiers in Microbiology, 2018
The proper timing and positioning of cytokinesis/septation is crucial for hyphal growth and conidiation in Aspergillus nidulans. The septation initiation network (SIN) components are a conserved spindle pole body (SPB) localized signaling cascade and the
Ping Jiang, Shujun Zheng, Ling Lu
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High DAPK1 Expression Promotes Tumor Metastasis of Gastric Cancer

Biology, 2022
Gastric cancer (GC) is a common upper gastrointestinal tumor. Death-associated protein kinase (DAPK1) was found to participate in the development of various malignant tumors. However, there are few reports on DAPK1 in gastric cancer.
Qingshui Wang, Shuyun Weng, Yuqin Sun, Youyu Lin, Wenting Zhong, Hang Fai Kwok, Yao Lin   +6 more
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Analysis of the Plasmid-Based ts-Mutant ΔfabA/pTS-fabA Reveals Its Lethality under Aerobic Growth Conditions That Is Suppressed by Mild Overexpression of desA at a Restrictive Temperature in Pseudomonas aeruginosa

Microbiology Spectrum, 2023
It is uncertain whether PA1610|fabA is essential or dispensable for growth on LB-agar plates under aerobic conditions in Pseudomonas aeruginosa PAO1.
Liyan Tian, Zhili Yang, Jianxin Wang, Jianhua Liu   +3 more
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Characterization of Curtovirus V2 Protein, a Functional Homolog of Begomovirus V2

Frontiers in Plant Science, 2020
Geminiviruses are single-stranded DNA plant viruses with circular genomes packaged within geminate particles. Among the Geminiviridae family, Begomovirus and Curtovirus comprise the two best characterized genera.
Ana P. Luna, Beatriz Romero-Rodríguez, Tábata Rosas-Díaz, Laura Cerero, Edgar A. Rodríguez-Negrete, Araceli G. Castillo, Eduardo R. Bejarano   +6 more
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Identification of the Potential Virulence Factors and RNA Silencing Suppressors of Mulberry Mosaic Dwarf-Associated Geminivirus

Viruses, 2018
Plant viruses encode virulence factors or RNA silencing suppressors to reprogram plant cellular processes or to fine-tune host RNA silencing-mediated defense responses.
Xiuling Yang, Yanxiang Ren, Shaoshuang Sun, Dongxue Wang, Fanfan Zhang, Dawei Li, Shifang Li, Xueping Zhou   +7 more
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Hsa_circ_0043278 Inhibits Tumorigenesis and is Downregulated in Colorectal Cancer

Cancer Management and Research, 2021
Jiali Wang,1,2 Tiangong Wang,2 Shiyun Hu,2 Jinyun Li,1 Chao Ni,1 Meng Ye1 1Department of Oncology and Hematology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, People’s Republic of China; 2School of Medicine, Ningbo ...
Wang J, Wang T, Hu S, Li J, Ni C, Ye M
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