Results 11 to 20 of about 1,053,068 (399)

The conversion of amber suppressors to ochre suppressors. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1968
Amber suppressors conversion to ochre suppressors in RNA of bacterium or bacteriophage using uracil ...
Mary Osborn, Stanley Person
openaire   +3 more sources

Tumor suppressors: enhancers or suppressors of regeneration? [PDF]

open access: yesDevelopment, 2013
Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue regeneration, focusing on the evolutionarily conserved tumor suppressors pRb1, p53, Pten and Hippo.
Jason H. Pomerantz, Helen M. Blau
openaire   +3 more sources

Is PML a Tumor Suppressor? [PDF]

open access: yesFrontiers in Oncology, 2013
The role of the promyelocytic leukemia (PML) protein has been widely tested in many different contexts, as attested by the hundreds of papers present in the literature. In most of these studies, PML is regarded as a tumor suppressor, a notion on the whole accepted by the scientific community.
M. Mazza, P.G. Pelicci
openaire   +4 more sources

Suppressors of selection

open access: yesPLOS ONE, 2017
Inspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present examples of undirected structures acting as suppressors of selection for any fitness value r > 1. This means that the average fixation probability of an advantageous mutant or invader individual placed at some node is
Fernando Alcalde Cuesta   +2 more
openaire   +9 more sources

Design and Characteristic Analysis of a New Type of Hydraulic Pulsation Suppressor [PDF]

open access: yesE3S Web of Conferences, 2021
In order to decrease the pressure pulsation of high-pressure hydraulic system and speed up the process of high-pressure hydraulic system, a new type of hydraulic pulsation suppressor is designed.
Yuan Jun   +6 more
doaj   +1 more source

Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants [PDF]

open access: yes, 2009
The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an ...
Goldbach, R.W.   +5 more
core   +2 more sources

Glucose Transporters and Virulence in Leishmania mexicana

open access: yesmSphere, 2018
Glucose transporters are important for viability and infectivity of the disease-causing amastigote stages of Leishmania mexicana. The Δgt1-3 null mutant, in which the 3 clustered glucose transporter genes, GT1, GT2, and GT3, have been deleted, is ...
Xiuhong Feng   +4 more
doaj   +1 more source

Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer

open access: yesCells, 2020
The emergence of immunotherapy has been an astounding breakthrough in cancer treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have shown remarkable therapeutic outcomes.
Andrew M. K. Law   +2 more
semanticscholar   +1 more source

A Suppressor/Avirulence Gene Combination in Hyaloperonospora arabidopsidis Determines Race Specificity in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2018
The pathosystem of Arabidopsis thaliana and diploid biotrophic oomycete Hyaloperonospora arabidopsidis (Hpa) has been a model for investigating the molecular basis of Flor's gene-for-gene hypothesis.
Alison Woods-Tör   +5 more
doaj   +1 more source

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