Results 271 to 280 of about 880,593 (358)

miRNA and Its Implications in the Treatment Resistance in Breast Cancer-Narrative Review of What Do We Know So Far. [PDF]

Noncoding RNA
Komporaly IA, Gheorghe AS, Kajanto LA, Iovănescu EA, Georgescu B, Mihăilă RI, Radu AM, Zob DL, Mihai MM, Georgescu MT, Stănculeanu DL.   +10 more
europepmc   +1 more source

Faculty Opinions recommendation of ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.

, 2018
Stephen D. Nimer
openalex   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Differential Expression of Key Oncogenic and Tumor Suppressor MicroRNAs Induced by Andrographolide in Androgen-Independent PC3 and Androgen-Dependent LNCaP Prostate Cancer Cells. [PDF]

Genes (Basel)
Sahare P, Bravo-Vázquez LA, Veloz-Briones DA, Bernal-Vázquez D, Bolaños-Fernández I, Anguiano B, Luna-Bárcenas G, Paul S.   +7 more
europepmc   +1 more source

eLife Assessment: Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism [PDF]

Yaoting Ji
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Correction: Receptor tyrosine kinase inhibitor sunitinib as novel immunotherapy to inhibit myeloid-derived suppressor cells for treatment of endometriosis. [PDF]

Front Immunol
He Y, Hung SW, Liang B, Zhang R, Gao Y, Chu CY, Zhang T, Xu H, Chung JPW, Wang CC.   +9 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

HypoxamiRs in pancreatic cancer: master regulators of the hypoxic tumor microenvironment. [PDF]

Cell Biol Toxicol
Salehi-Sangani P, Maharati AH, Payami B, Aliakbarian M, Abbaszadegan MR.   +4 more
europepmc   +1 more source

Characterization of Arabidopsis thaliana Light Mutants Identified in lrb1 lrb2 Suppressor Genetic Screens

, 2015
Weston Orendorff, Kevin Mayer
openalex   +1 more source