Results 21 to 30 of about 17,879 (182)

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

Frontiers in Neuroscience, 2022
Individuals suffering from mood and anxiety disorders often show significant disturbances in sleep and circadian rhythms. Animal studies indicate that circadian rhythm disruption can cause increased depressive- and anxiety-like behavior, but the ...
Chelsea A. Vadnie, Kaitlyn A. Petersen, Lauren A. Eberhardt, Mariah A. Hildebrand, Allison J. Cerwensky, Hui Zhang, Jennifer N. Burns, Darius D. Becker-Krail, Lauren M. DePoy, Ryan W. Logan, Colleen A. McClung   +10 more
doaj   +1 more source

Paradoxical Sleep Suppresses Immediate Early Gene Expression in the Rodent Suprachiasmatic Nuclei

Frontiers in Neurology, 2010
Light stimulates neuronal activity with subsequent expression of the protein product of the immediate early gene, c-fos, in the Suprachiasmatic Nuclei (SCN). Non-photic stimuli is also thought to modulate activity within the SCN.
Michael J Decker, Michael J Decker, Michael J Decker, David B Rye, Shih-Yu Lee, Kingman P Strohl   +5 more
doaj   +1 more source

Circadian rhythm of PERIOD2::LUCIFERASE expression in the trigeminal ganglion of mice

Frontiers in Neuroscience, 2023
IntroductionThe trigeminal nerve conveys delicate sensations such as warmth, pain, and tactile pressure in the oral and facial regions, and most trigeminal afferent cell bodies are located in the trigeminal ganglion.
Yukie Shirakawa, Sachi N. Ohno, Kanae A. Yamagata, Eriko Kuramoto, Yoshiaki Oda, Takahiro J. Nakamura, Wataru Nakamura, Mitsutaka Sugimura   +7 more
doaj   +1 more source

Mathematical model of the interaction between the dorsal and ventral regions of the suprachiasmatic nucleus of rats

Sleep Science, 2010
Background and objective: In mammals, the main biological clock that is synchronized by light is located in the suprachiasmatic nucleus of the hypothalamus, which can be divided into two distinct regions: the ventrolateral and the ...
Bruno da Silva Brandão Gonçalves, Breno Tercio Santos Carneiro, Crhistiane Andressa da Silva, Diego Alexandre da Cunha Fernandes, Fabiano Santos Fortes, João Miguel Gonçalves Ribeiro, Rafaela Cobuci Cerqueira, Sergio Arthuro Mota Rolim, John Fontenele Araújo   +8 more
doaj   +1 more source

Modulating effect of irisin on the functional state of inhibitory afferent inputs to the suprachiasmatic nucleus from the arcuate nucleus [PDF]

BIO Web of Conferences
In vitro experiments on viable hypothalamic slices of male Wistar rats, the modulating effect of the myokine irisin on the parameters of inhibitory responses of neurons in the suprachiasmatic nucleus to stimulation of the arcuate nucleus was studied.
Inyushkin Alexey, Pavlenko Snezhanna, Isakova Tatiana, Konashenkova Anastasia, Inyushkina Elena   +4 more
doaj   +1 more source

The Hypothalamus of the Beaked Whales: The Paraventricular, Supraoptic, and Suprachiasmatic Nuclei

Biology, 2023
The hypothalamus is the body’s control coordinating center. It is responsible for maintaining the body’s homeostasis by directly influencing the autonomic nervous system or managing hormones. Beaked whales are the longest divers among cetaceans and their
Simona Sacchini, Cristiano Bombardi, Manuel Arbelo, Pedro Herráez   +3 more
doaj   +1 more source

Stereotaxic Surgery for Suprachiasmatic Nucleus Lesions in Mice

Bio-Protocol, 2017
Site-specific lesions are invaluable methods for investigating the function of brain regions within the central nervous system and can be used to study neural mechanisms of behaviors. Precise stereotaxic surgery is required to lesion small regions of the
Kimiko Shimizu, Yoshitaka Fukada
doaj   +1 more source

Identification of the suprachiasmatic nucleus venous portal system in the mammalian brain

Nature Communications, 2021
The first known portal system in the mammalian brain was identified in 1933. Here the authors describe a new portal system between the capillary beds of the Suprachiasmatic Nucleus master clock and a circumventricular organ, enabling humoral signals to ...
Yifan Yao, Alana B’nai Taub, Joseph LeSauter, Rae Silver   +3 more
doaj   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source