In Synch but Not in Step: Circadian Clock Circuits Regulating Plasticity in Daily Rhythms [PDF]
The suprachiasmatic nucleus (SCN) is a network of neural oscillators that program daily rhythms in mammalian behavior and physiology. Over the last decade much has been learned about how SCN clock neurons coordinate together in time and space to form a ...
Evans, Jennifer A., Gorman, M. R.
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Circadian rhythm of PERIOD2::LUCIFERASE expression in the trigeminal ganglion of mice
IntroductionThe trigeminal nerve conveys delicate sensations such as warmth, pain, and tactile pressure in the oral and facial regions, and most trigeminal afferent cell bodies are located in the trigeminal ganglion.
Yukie Shirakawa +7 more
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Circadian regulation of reproduction: From gamete to offspring [PDF]
P01326625; Grants: GNT0519315Few challenges are more critical to the survival of a species than reproduction. To ensure reproductive success, myriad aspects of physiology and behaviour need to be tightly orchestrated within the animal, as well as timed ...
Boden, M., Kennaway, D., Varcoe, T.
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Output from VIP cells of the mammalian central clock regulates daily physiological rhythms [PDF]
The suprachiasmatic nucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and behaviour. The roles of the various SCN cell types in communicating timing information to downstream physiological systems remain ...
A Kalsbeek +70 more
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Shell Neurons of the Master Circadian Clock Coordinate the Phase of Tissue Clocks Throughout the Brain and Body [PDF]
Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined.
Baba, Kenkichi +14 more
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Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels [PDF]
There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is widely recognized as the dominant pacemaker of the circadian system, we have ...
Almeida, OFX +5 more
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Paradoxical Sleep Suppresses Immediate Early Gene Expression in the Rodent Suprachiasmatic Nuclei
Light stimulates neuronal activity with subsequent expression of the protein product of the immediate early gene, c-fos, in the Suprachiasmatic Nuclei (SCN). Non-photic stimuli is also thought to modulate activity within the SCN.
Michael J Decker +5 more
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The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus. [PDF]
The neural activity patterns of suprachiasmatic nucleus (SCN) neurons are dynamically regulated throughout the circadian cycle with highest levels of spontaneous action potentials during the day.
Block, Gene D +2 more
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Modulating effect of irisin on the functional state of inhibitory afferent inputs to the suprachiasmatic nucleus from the arcuate nucleus [PDF]
In vitro experiments on viable hypothalamic slices of male Wistar rats, the modulating effect of the myokine irisin on the parameters of inhibitory responses of neurons in the suprachiasmatic nucleus to stimulation of the arcuate nucleus was studied.
Inyushkin Alexey +4 more
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Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
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