Results 21 to 30 of about 34,337 (216)

Hypomorphic Expression of Pitx3 Disrupts Circadian Clocks and Prevents Metabolic Entrainment of Energy Expenditure

Cell Reports, 2019
Summary: Daily adaptation of metabolic activity to light-dark cycles to maintain homeostasis is controlled by hypothalamic nuclei receiving information from the retina and from nutritional inputs that vary according to feeding cycles.
Almudena del Río-Martín, Iara Pérez-Taboada, Antonio Fernández-Pérez, Rosario Moratalla, Pedro de la Villa, Mario Vallejo   +5 more
doaj   +1 more source

Circadian regulation of reproduction: From gamete to offspring [PDF]

, 2013
P01326625; Grants: GNT0519315Few challenges are more critical to the survival of a species than reproduction. To ensure reproductive success, myriad aspects of physiology and behaviour need to be tightly orchestrated within the animal, as well as timed ...
Boden, M., Kennaway, D., Varcoe, T.
core   +1 more source

Output from VIP cells of the mammalian central clock regulates daily physiological rhythms [PDF]

, 2020
The suprachiasmatic nucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and behaviour. The roles of the various SCN cell types in communicating timing information to downstream physiological systems remain ...
A Kalsbeek, A Kalsbeek, A Kalsbeek, A Schroeder, AC West, AG Watts, AG Watts, AH Cheng, AJ Harmar, AT Hughes, C Gizowski, C Mazuski, CA Feillet, CS Colwell, DA Bechtold, DF Manvich, DH Loh, DJ Cutler, EE Abrahamson, ES Lein, ES Maywood, FK Stephan, H Taniguchi, H Wakamatsu, HT VanderLeest, HT vanderLeest, I Kallo, IT Lee, J Fahrenkrug, J Fan, J Hannibal, J Schaap, JA Evans, JA Evans, JE Quintero, JL Gomez, JR Jones, JR Jones, K Tanaka, L Hanna, L Madisen, L Mei, LD Alexander, LP Morin, LP Morin, M Howarth, M Mieda, MC Garnica-Siqueira, MJ Krashes, MR Ralph, MS Jasper, N Nunn, N Yamaguchi, P Indic, R Enoki, RL Spencer, RM Buijs, RY Moore, S Itoh, S Paul, SJ Aton, SK Lee, T Ikeno, T Kalamatianos, TJ Nakamura, TM Brown, TM Brown, TM Brown, TM Brown, TO Hermanstyne, WD Todd   +70 more
core   +1 more source

Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels [PDF]

, 1997
There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is widely recognized as the dominant pacemaker of the circadian system, we have ...
Almeida, OFX, Andrade, JP, Lieberman, AR, Madeira, MD, Paula-Barbosa, MM, Sousa, N   +5 more
core   +1 more source

The presence of neuronal-specific nuclear protein (NeuN) in the circadian timing system of the capuchin monkey (Cebus apella)

Sleep Science, 2010
Background and objective: The circadian timing system (CTS) is composed of a group of specialized neuronal structures that establish a temporal organization of physiological and behavioral processes within precise patterns.
Rayane Bartira Silva do Nascimento, Janaína Siqueira Borda, Rovena Clara Galvão Januário Engelberth, Raysa Oliveira de Medeiros, Renata Frazão, Luciana Pinato, André Luiz Bezerra de Pontes, Expedito Silva do Nascimento, Maria Inês Nogueira, Roelf Justino Cruz-Rizzolo, Miriam Stela Maris de Oliveira Costa, Jeferson de Souza Cavalcante   +11 more
doaj   +1 more source

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

Frontiers in Neuroscience, 2022
Individuals suffering from mood and anxiety disorders often show significant disturbances in sleep and circadian rhythms. Animal studies indicate that circadian rhythm disruption can cause increased depressive- and anxiety-like behavior, but the ...
Chelsea A. Vadnie, Kaitlyn A. Petersen, Lauren A. Eberhardt, Mariah A. Hildebrand, Allison J. Cerwensky, Hui Zhang, Jennifer N. Burns, Darius D. Becker-Krail, Lauren M. DePoy, Ryan W. Logan, Colleen A. McClung   +10 more
doaj   +1 more source

Shell Neurons of the Master Circadian Clock Coordinate the Phase of Tissue Clocks Throughout the Brain and Body [PDF]

, 2015
Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined.
Baba, Kenkichi, Baker, Kimberly M., Bartness, Timothy J., Callif, Ben L., Castanon-Cervantes, Oscar, Davidson, Alec J., Ehlen, J. Christopher, Evans, Jennifer A., Kloehn, Ian, Leise, Tanya, Mitchell, Andrew S., Paul, Ketema N., Suen, Ting-Chung, Teubner, Brett J.W., Tosini, Gianluca   +14 more
core   +2 more sources

Circadian rhythm of PERIOD2::LUCIFERASE expression in the trigeminal ganglion of mice

Frontiers in Neuroscience, 2023
IntroductionThe trigeminal nerve conveys delicate sensations such as warmth, pain, and tactile pressure in the oral and facial regions, and most trigeminal afferent cell bodies are located in the trigeminal ganglion.
Yukie Shirakawa, Sachi N. Ohno, Kanae A. Yamagata, Eriko Kuramoto, Yoshiaki Oda, Takahiro J. Nakamura, Wataru Nakamura, Mitsutaka Sugimura   +7 more
doaj   +1 more source

The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus. [PDF]

, 2015
The neural activity patterns of suprachiasmatic nucleus (SCN) neurons are dynamically regulated throughout the circadian cycle with highest levels of spontaneous action potentials during the day.
Block, Gene D, Colwell, Christopher S, Kudo, Takashi   +2 more
core   +1 more source

Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]

, 2015
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA, Quartini, Adele, Tirassa, Paola   +2 more
core   +2 more sources