Voluntary exercise can strengthen the circadian system in aged mice [PDF]
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
A Davidson +74 more
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The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]
This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Baudelot +51 more
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The Hypothalamus of the Beaked Whales: The Paraventricular, Supraoptic, and Suprachiasmatic Nuclei
The hypothalamus is the body’s control coordinating center. It is responsible for maintaining the body’s homeostasis by directly influencing the autonomic nervous system or managing hormones. Beaked whales are the longest divers among cetaceans and their
Simona Sacchini +3 more
doaj +1 more source
Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
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Identification of the suprachiasmatic nucleus venous portal system in the mammalian brain
The first known portal system in the mammalian brain was identified in 1933. Here the authors describe a new portal system between the capillary beds of the Suprachiasmatic Nucleus master clock and a circumventricular organ, enabling humoral signals to ...
Yifan Yao +3 more
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Acute knockdown of Kv4.1 regulates repetitive firing rates and clock gene expression in the suprachiasmatic nucleus and daily rhythms in locomotor behavior [PDF]
Rapidly activating and inactivating A-type K+currents (IA) encoded by Kv4.2 and Kv4.3 pore-forming (α) subunits of the Kv4 subfamily are key regulators of neuronal excitability.
Granados-Fuentes, Daniel +4 more
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Alterations of clock gene RNA expression in brain Regions of a triple transgenic model of Alzheimer's Disease [PDF]
A disruption to circadian rhythmicity and the sleep/wake cycle constitutes a major feature of Alzheimer's disease (AD). The maintenance of circadian rhythmicity is regulated by endogenous clock genes and a number of external Zeitgebers, including light ...
@corresponding, Author +14 more
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Stereotaxic Surgery for Suprachiasmatic Nucleus Lesions in Mice
Site-specific lesions are invaluable methods for investigating the function of brain regions within the central nervous system and can be used to study neural mechanisms of behaviors. Precise stereotaxic surgery is required to lesion small regions of the
Kimiko Shimizu, Yoshitaka Fukada
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FORMATION OF BIOLOGICAL RHYTHMS IN PRENATAL HUMAN ONTOGENESIS
The formation of biological rhythms in prenatal period is associated with ontogenesis of suprachiasmatic nucleus of the hypothalamus and pineal gland, activity of micro-RNA and clock genes.
V.P. Pishak
doaj +1 more source
The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]
The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M. +10 more
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