Results 11 to 20 of about 351,767 (188)

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses [PDF]

open access: yesNature Communications, 2020
The suprachiasmatic nucleus (SCN) ensures rhythmic electrical activity that varies between day and night to determine circadian behaviours. The authors show that TRESK channels provide a feedback mechanism to maintain the SCN in the appropriate state for
Tatjana Lalic   +7 more
doaj   +2 more sources

The suprachiasmatic nucleus [PDF]

open access: yesCurrent Biology, 2018
Like it or not, your two suprachiasmatic nuclei (SCN) govern your life: from when you wake up and fall asleep, to when you feel hungry or can best concentrate. Each is composed of approximately 10,000 tightly interconnected neurons, and the pair sit astride the mid-line third ventricle of the hypothalamus, immediately dorsal to the optic chiasm (Figure
Andrew P, Patton, Michael H, Hastings
openaire   +2 more sources

GABAergic signalling in the suprachiasmatic nucleus is required for coherent circadian rhythmicity. [PDF]

open access: yesEur J Neurosci
The suprachiasmatic nucleus is the circadian pacemaker of the mammalian brain. Suprachiasmatic nucleus neurons display synchronization of their firing frequency on a circadian timescale, which is required for the pacemaker function of the suprachiasmatic
Klett N   +9 more
europepmc   +2 more sources

Ex vivo Comparative Investigation of Suprachiasmatic Nucleus Excitotoxic Resiliency [PDF]

open access: yes, 2022
This dataset is CC0. Histology images and excel files with the data generated by analyzing the images associated with the paper Ex vivo Comparative Investigation of Suprachiasmatic Nucleus Excitotoxic ...
Acharyya, Debalina, Prosser, Rebecca
core   +1 more source

Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations

open access: yesNature Communications, 2020
Cell groups in the hypothalamic suprachiasmatic clock contribute to the genesis of circadian rhythms. The authors identified two populations of vasoactive intestinal polypeptide-expressing neurons in the suprachiasmatic nucleus which regulate locomotor ...
William D. Todd   +13 more
doaj   +1 more source

A Journey in the Brain’s Clock: In Vivo Veritas?

open access: yesBiology, 2023
The suprachiasmatic nuclei (SCN) of the hypothalamus contain the circadian pacemaker that coordinates mammalian rhythms in tune with the day-night cycle.
Alec J. Davidson   +2 more
doaj   +1 more source

Long-lasting effects of sepsis on circadian rhythms in the mouse. [PDF]

open access: yesPLoS ONE, 2012
Daily patterns of activity and physiology are termed circadian rhythms and are driven primarily by an endogenous biological timekeeping system, with the master clock located in the suprachiasmatic nucleus.
Emma K O'Callaghan   +3 more
doaj   +1 more source

Global parameter search reveals design principles of the mammalian circadian clock [PDF]

open access: yes, 2008
Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
Locke, James C. W.   +3 more
core   +1 more source

Masking effect in rats bearing partial lesions of the suprachiasmatic nucleus

open access: yesSleep Science, 2010
Background and objective: To explore the role of the suprachiasmatic nucleus (SCN) for masking by light in rats bearing bilateral complete or partial lesions of the suprachiasmatic nucleus. Methods: Rats were submitted to electrolytic SCN
Manuel Ángeles-Castellanos   +3 more
doaj   +1 more source

Hypomorphic Expression of Pitx3 Disrupts Circadian Clocks and Prevents Metabolic Entrainment of Energy Expenditure

open access: yesCell Reports, 2019
Summary: Daily adaptation of metabolic activity to light-dark cycles to maintain homeostasis is controlled by hypothalamic nuclei receiving information from the retina and from nutritional inputs that vary according to feeding cycles.
Almudena del Río-Martín   +5 more
doaj   +1 more source

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