Results 51 to 60 of about 17,879 (182)
Imaging Individual Differences in the Response of the Human Suprachiasmatic Area to Light
Frontiers in Neurology, 2018 Circadian disruption is associated with poor health outcomes, including sleep and mood disorders. The suprachiasmatic nucleus (SCN) of the anterior hypothalamus acts as the master biological clock in mammals, regulating circadian rhythms throughout the ...
Elise M. McGlashan +6 more
doaj +1 more source
Nature Communications, 2020 Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al.
Andrew P. Patton +7 more
doaj +1 more source
Circadian actions of melatonin at the suprachiasmatic nucleus [PDF]
Behavioural Brain Research, 1995 The biological clock in the suprachiasmatic nucleus (SCN) of the hypothalamus plays a well-defined role in regulating melatonin production by the pineal. Emerging evidence indicates that melatonin itself can feed back upon the SCN and thereby influence circadian functions.
M U, Gillette, A J, McArthur
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The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
Seasonal changes in the suprachiasmatic nucleus of man [PDF]
Neuroscience Letters, 1992 The mammalian suprachiasmatic nucleus (SCN) is considered to be the principal component of the biological clock, generating a wide variety of physiological and behavioral circadian rhythms. In addition to its implication in circadian rhythms, the SCN is also involved in the expression of some seasonal cycles.
Hofman, M.A., Swaab, D.F.
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak +6 more
wiley +1 more source
Retino-hypothalamic regulation of light-induced murine sleep
Frontiers in Systems Neuroscience, 2014 The temporal organization of sleep is regulated by an interaction between the circadian clock and homeostatic processes. Light indirectly modulates sleep through its ability to phase shift and entrain the circadian clock.
Fanuel eMuindi +4 more
doaj +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health is recognized as a key component of diabetes management, there has been less emphasis on nighttime light exposure. This study aimed to investigate the effects of blue and white light exposure immediately prior to
Seok Jin Hong +5 more
wiley +1 more source
Nutrition Bulletin, EarlyView.ABSTRACT Shift work is associated with insulin resistance, dyslipidaemia and metabolic syndrome, but how consecutive meals at the same clock times differentially shape postprandial metabolism in day‐ and night‐shifts remains unclear. This study used a unique simulated shift work intervention with four consecutive meals and high‐resolution sampling to ...
Ameena M. Khan Sullivan +4 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena +4 more
wiley +1 more source