Results 41 to 50 of about 29,423 (147)

Apraxia and motor dysfunction in corticobasal syndrome [PDF]

, 2014
Background: Corticobasal syndrome (CBS) is characterized by multifaceted motor system dysfunction and cognitive disturbance; distinctive clinical features include limb apraxia and visuospatial dysfunction. Transcranial magnetic stimulation (TMS) has been
A Alberici, A Kertesz, A Kertesz, A Zwinkels, AA Kühn, AK Holl, Alessio Avenanti, B Borroni, B Okuda, BF Boeve, BF Boeve, BP Shelley, C Zadikoff, CD Good, D Claus, D Rueckert, DS Margulies, E De Renzi, E Frasson, E Mioshi, ED Huey, G Goldenberg, G Goldenberg, G Pengas, H Ling, J Ashburner, J Gottlieb, J Rohrer, J Valls-Solé, James R. Burrell, JL Whitwell, JM Cedarbaum, JO Rinne, John R. Hodges, JR Burrell, JR Burrell, JR Burrell, JR Burrell, K Tsuchiya, KA Josephs, KY Haaland, LJ Buxbaum, LJG Rothi, LR Robinson, M Heath, M Hornberger, M Pazzaglia, Matthew C. Kiernan, MC Kiernan, Michael Hornberger, NL Graham, NL Graham, P Soliveri, PK Pal, PP Pramstaller, PS Mathuranath, QJ Almeida, R Cantello, R Chen, R Leiguarda, R Leiguarda, R Mathew, R Mathew, RG Gross, RJ Fisher, RT Watson, S Vucic, S Vucic, S Vucic, S Vucic, SE Lee, SM Smith, SM Smith, Steve Vucic, T Fukui, U Ziemann, V Di Lazzaro, V Stamenova, Y Okuma, Y Zhang   +79 more
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Development and validation of the automated imaging differentiation in parkinsonism (AID-P): a multicentre machine learning study

The Lancet: Digital Health, 2019
Summary: Background: Development of valid, non-invasive biomarkers for parkinsonian syndromes is crucially needed. We aimed to assess whether non-invasive diffusion-weighted MRI can distinguish between parkinsonian syndromes using an automated imaging ...
Derek B Archer, PhD, Justin T Bricker, MS, Winston T Chu, BS, Roxana G Burciu, PhD, Johanna L McCracken, BS, Song Lai, ProfPhD, Stephen A Coombes, PhD, Ruogu Fang, PhD, Angelos Barmpoutis, PhD, Daniel M Corcos, PhD, Ajay S Kurani, PhD, Trina Mitchell, MS, Mieniecia L Black, MPH, Ellen Herschel, BS, Tanya Simuni, ProfMD, Todd B Parrish, ProfPhD, Cynthia Comella, ProfMD, Tao Xie, MD, Klaus Seppi, ProfMD, Nicolaas I Bohnen, ProfMD, Martijn LTM Müller, PhD, Roger L Albin, ProfMD, Florian Krismer, MD, Guangwei Du, MD, Mechelle M Lewis, PhD, Xuemei Huang, ProfMD, Hong Li, PhD, Ofer Pasternak, PhD, Nikolaus R McFarland, MD, Michael S Okun, ProfMD, David E Vaillancourt, ProfPhD   +30 more
doaj   +1 more source

Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]

, 2017
Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger, Alcalay, Roy N., Babcock, Debra, Bowman, F. DuBois, Chen-Plotkin, Alice, David, Karen K., Dawson, Ted M., Dewey, Richard B., Jr., Foroud, Tatiana, German, Dwight, Gwinn, Katrina, Huang, Xuemei, Lungu, Codrin, Petyuk, Vlad, Potashkin, Judith A., Rosenthal, Liana S., Saunders-Pullman, Rachel, Scherzer, Clemens R., Sieber, Beth-Anne, St Hillaire-Clarke, Coryse, Sutherland, Margaret, Swanson-Fischer, Christine, Vaillancourt, David E., Walt, David R., West, Andrew B., Zhang, Jing   +25 more
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Understanding fatigue in progressive supranuclear palsy

Scientific Reports, 2021
Fatigue is a common and disabling non-motor symptom (NMS) of Parkinson’s disease (PD); however, it has been poorly understood in patients with progressive supranuclear palsy (PSP).
Jong Hyeon Ahn, Joomee Song, Dong Yeong Lee, Jinyoung Youn, Jin Whan Cho   +4 more
doaj   +1 more source

Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. [PDF]

, 2014
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls.
Hardy, J, Holton, JL, Houlden, H, Kara, E, Lees, AJ, Ling, H, Martino, D, Plant, GT, Revesz, T   +8 more
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Clinical features of supranuclear palsy

Бюллетень сибирской медицины, 2009
Progressive supranuclear palsy related to neurodegenerative diseases of the brain. In the pathological process involved, and stem structure. The disease manifests a combination of progressive akinetic-rigid syndrome and early development of postural ...
T. A. Valikova, V. M. Alifirova, N. V. Pugachenko, R. B. Tsyrenzhapova, A. B. Bichik   +4 more
doaj   +1 more source

Variation at the TRIM11 Locus Modifies Progressive Supranuclear Palsy Phenotype [PDF]

, 2018
Objective The basis for clinical variation related to underlying progressive supranuclear palsy (PSP) pathology is unknown. We performed a genome‐wide association study (GWAS) to identify genetic determinants of PSP phenotype.
Armstrong, Blauwendraat, Chang, Chen, Coetzee, Daniel, Galvin, Giambartolomei, Gong, Hassan, Hatakeyama, Hawrylycz, Hoglinger, Hoglinger, Hughes, Kontaxi, Lambert, Lassot, Leeuw, Ling, Litvan, Magiera, Maston, Morris, Murthy, Myeku, Nath, Ramasamy, Reed, Respondek, Sanders, Schrag, Steele, Takahashi, Williams, Williams, Williams, Ying, Young, Zhang   +39 more
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The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. [PDF]

, 2015
Chronic traumatic encephalopathy (CTE) is a neurodegeneration characterized by the abnormal accumulation of hyperphosphorylated tau protein within the brain. Like many other neurodegenerative conditions, at present, CTE can only be definitively diagnosed
Alvarez, Victor E, Bieniek, Kevin F, Cairns, Nigel J, Crary, John F, Dams-O'Connor, Kristen, Dickson, Dennis W, Folkerth, Rebecca D, Gordon, Wayne A, Keene, C Dirk, Litvan, Irene, McKee, Ann C, Perl, Daniel P, Stein, Thor D, Stewart, William, TBI/CTE group, Tripodis, Yorghos, Vonsattel, Jean-Paul   +16 more
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Progressive supranuclear palsy: A case report and brief review of the literature

Radiology Case Reports
Atypical Parkinsonian syndromes are a subset of progressive neurodegenerative disorders that present with signs of Parkinson's disease. However, due to multisystem degeneration, the atypical Parkinsonian syndromes have additional symptoms that are often ...
Vivek Batheja, MD, Morgan Fish, DO, Aneri B. Balar, MD, Jeffery P. Hogg, MD, FACR, Dhairya A. Lakhani, MD, Musharaf Khan, DO   +5 more
doaj   +1 more source

Affective symptoms in progressive supranuclear palsy

Journal of Geriatric Mental Health, 2014
Progressive supranuclear palsy is an unusual neurodegenerative disorder, which superficially resembles Parkinson′s disease, and the initial manifestations are characterized by depression, akinesia and mild cognitive impairment.
K S Shaji, K S Jyothi
doaj   +1 more source