Results 91 to 100 of about 13,268 (215)

Developmental hypomyelination in Wolfram syndrome: New insights from neuroimaging and gene expression analyses [PDF]

, 2019
Wolfram syndrome is a rare multisystem disorder caused by mutations in WFS1 or CISD2 genes leading to brain structural abnormalities and neurological symptoms. These abnormalities appear in early stages of the disease.
Dougherty, Joseph, Hershey, Tamara, Marshall, Bess, Neyman, Olga, Park, Ki Yun, Rahn, Rachel, Samara, Ahmad, Samara, Amjad   +7 more
core   +1 more source

Nesfatin-1, a unique regulatory neuropeptide of the brain [PDF]

, 2012
Nesfatin-1, a newly discovered NUCB2-derived satiety neuropeptide is expressed in several neurons of forebrain, hindbrain, brainstem and spinal cord. This novel anorexigenic substance seems to play an important role in hypothalamic pathways regulating ...
Bajor, Grzegorz, Czajkowska, Beata, Kostro, Karol, Krzystanek, Marek, Palasz, Artur, Wiaderkiewicz, Ryszard, Worthington, John   +6 more
core   +1 more source

STUDY OF UNITARY ACTIVITY IN THE SUPRAOPTIC NUCLEUS OF THE HYPOTHALAMUS

The Japanese Journal of Physiology, 1963
Activity in hypothalamic supraoptic nuclear cells was recorded with microelectrodes in hemispherectomized, chloralose-anesthetized cats. Repetitive stimulations of skin afferents augmented activity of some units but inhibited others. Activity of units was little affected by decortication and removal of the caudate nucleus but considerably increased by ...
SUDA, Isamu, KOIZUMI, Kiyomi, BROOKS, Chandler C.   +2 more
openaire   +3 more sources

Cortical Type: The Basis for a Modern Neurodevelopmental Synthesis (Ontogeny, Phylogeny, Synaptic Connectivity) of the Human Cerebral Cortex

Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.
The parcellation of cortical types along the gradient of laminar complexity of the human cerebral cortex provides the basis for a Modern Neurodevelopmental Synthesis. This synthesis integrates ontogeny, phylogeny, gene expression, receptor architecture, cellular features, and synaptic connectivity and aims to guide experimental design for human ...
Josefa Zaldivar‐Diez, Miguel Ángel García‐Cabezas   +1 more
wiley   +1 more source

Colocalization of connexin 36 and corticotropin-releasing hormone in the mouse brain [PDF]

, 2009
Background Gap junction proteins, connexins, are expressed in most endocrine and exocrine glands in the body and are at least in some glands crucial for the hormonal secretion.
Lars Westberg, Evelyn Sawa, Alice Y Wang, Lisa A Gunaydin, Ana C Ribeiro, Donald W Pfaff, L Michon, K Willecke, JI Nagy, G Sohl, RS Van Der Giessen, MM Kreuzberg, MA Ravier, PE Sawchenko, LW Swanson, LW Swanson, LW Swanson, MJ Brimble, DA Poulain, BW Connors, MV Bennett, GI Hatton, RD Andrew, P Cobbett, GI Hatton, H Arumugam, QZ Yang, S Gong, F Cicirata, G Sohl, M Palkovits, VW Tang, I Merchenthaler, SE Alves, SS Cui, C Peyron, RA Espana, C Dartsch, G Paxinos, JE Rash, P Cobbett, QZ Yang, DF Condorelli, R Parenti, CB Saper, JP Lara, Q Lei, S Yamada, S Cummings, MB Lassen   +49 more
core   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Dog With Meningoencephalitis of Unknown Etiology

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This report describes a case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a Maltese with meningoencephalitis of unknown etiology (MUE). The dog was treated with water restriction and tolvaptan, a vasopressin receptor antagonist, which resulted in an improvement in hyponatremia.
Yelim Lee, Jooyoung Park, Yeon Chae, Taesik Yun, Hakhyun Kim, Byeong‐Teck Kang   +5 more
wiley   +1 more source

Reaction of the Supraoptic Nucleus to Hypophysectomy.

Experimental Biology and Medicine, 1937
ConclusionEleostearic acid is quickly changed to a new acid in vivo. Distribution and metabolism of this acid has been followed by spectroscopic analysis and large differences found among several tissues.
openaire   +1 more source

Oxytocinergic Signaling in Zebrafish: Translational Perspectives for Autism Spectrum Disorder

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Alterations in oxytocin signaling are strongly implicated in the social and cognitive deficits characterizing Autism Spectrum Disorder (ASD) and other neurodevelopmental conditions. However, the precise mechanisms remain unclear. The zebrafish (Danio rerio) has emerged as a powerful translational model due to its evolutionarily conserved oxytocin ...
Géssica Peres, Melissa Talita Wiprich, Darlan Gusso, Carla Denise Bonan   +3 more
wiley   +1 more source

Immunocytochemical distribution of corticotropin-releasing hormone receptor type-1 (CRF(1))-like immunoreactivity in the mouse brain: light microscopy analysis using an antibody directed against the C-terminus. [PDF]

, 2000
Corticotropin-releasing hormone (CRH) receptor type 1 (CRF(1)) is a member of the receptor family mediating the effects of CRH, a critical neuromediator of stress-related endocrine, autonomic, and behavioral responses.
Baram, TZ, Brunson, KL, Cariaga, W, Chen, Y, Müller, MB   +4 more
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