Results 81 to 90 of about 13,268 (215)

Electrophysiology of hypothalamic magnocellular neurons in vitro: a rhythmic drive in organotypic cultures and acute slices

Frontiers in Neuroscience, 2016
Hypothalamic neurohormones are released in a pulsatile manner. The mechanisms of this pulsatility remain poorly understood and several hypotheses are available, depending upon the neuroendocrine system considered.
Jean-Marc eIsrael, Jean-Marc eIsrael, Stéphane H Oliet, Stéphane H Oliet, Philippe eCiofi, Philippe eCiofi   +5 more
doaj   +1 more source

Colocalization of oxytocin and phosphorylated form of elongation factor 2 in the rat hypothalamus [PDF]

, 2007
Oxytocin (OT) is one of the neuropituitary hormones and is synthesized in the neurons of the paraventricular nucleus (PVN) and supraoptic nucleus (SON). Previous studies have shown that the mRNAs encoding OT are delivered from the soma to both dendrites ...
Fujisawa, Toru, Matsui, Hideki, Matsushita, Masayuki, Moriwaki, Akiyoshi, Tomizawa, Kazuhito   +4 more
core   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Dysregulated Plasticity in Serotonin, Galanin, and Opioid Systems Contributes to Limbic Seizure Recruitment in Wistar Audiogenic Rat

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
To find molecular reasons why a genetic rat model (Wistar Audiogenic Rat, WAR) moves from sound‐triggered brainstem seizures to longer‐lasting limbic (temporal‐lobe) epilepsy after repeated loud‐noise exposure. WAR and normal Wistar rats received a 10‐day audiogenic kindling (twice‐daily loud noise).
Tays Araújo Camilo, Evandro Valentim‐Lima, José Antônio Cortes de Oliveira, Norberto Garcia‐Cairasco, Luís Carlos Reis, João Victor Nani, André de Souza Mecawi   +6 more
wiley   +1 more source

Effects of combined prenatal exposure to air pollution and maternal stress on social behavior and oxytocin and vasopressin systems in male and female mice

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Prenatal exposures to air pollution and maternal psychosocial stress are each associated with increased risk of neurodevelopmental disorders, including autism spectrum disorder (ASD), and epidemiological work suggests that concurrent exposure to these risk factors may be particularly harmful.
Maura C. Stoehr, Elise M. Martin, Joy T. Babalola, Jason Xue, Matthew J. Kern, Niki Y. Li, Madeline F. Winters, Sarvin Bhagwagar, Caroline J. Smith   +8 more
wiley   +1 more source

Effects of nitric oxide on magnocellular neurons of the supraoptic nucleus involve multiple mechanisms

Brazilian Journal of Medical and Biological Research, 2014
Physiological evidence indicates that the supraoptic nucleus (SON) is an important region for integrating information related to homeostasis of body fluids. Located bilaterally to the optic chiasm, this nucleus is composed of magnocellular neurosecretory
M.P. da Silva, P.L. Cedraz-Mercez, W.A. Varanda   +2 more
doaj   +1 more source

Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders

Cell & Bioscience, 2023
Oxytocin (OXT), produced and secreted in the paraventricular nucleus and supraoptic nucleus of magnocellular and parvocellular neurons. The diverse presence and activity of oxytocin suggests a potential for this neuropeptide in the pathogenesis and ...
Sen Zhang, Ying-Dan Zhang, Dong-Dong Shi, Zhen Wang   +3 more
doaj   +1 more source

Acute and persistent neuroendocrine and behavioral alterations after social fear conditioning in adolescent male mice

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Adolescence is a critical developmental period with heightened stress susceptibility. Traumatic experiences during this phase are highly predictive of future affective disorders, such as social anxiety disorder (SAD), which may manifest during early adolescence.
Anna Bludau, Melanie Kabas, Rohit Menon, Inga D. Neumann   +3 more
wiley   +1 more source

Fiber connections of the forel H-field as seen in marchi preparations [PDF]

, 1964
An anatomical study was made to follow the degeneration of fibers by means of Marchi technique in cat after making experimentally lesion in Forel H field. As the results the following conclusions were reached.
Mukawa, Jiro
core   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source