Results 81 to 90 of about 459,381 (230)

Microglia‐Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin

Advanced Science, Volume 12, Issue 6, February 10, 2025.
The susceptibility to stress in mice is enhanced by microglia‐derived vitamin D binding protein (VDBP). This effect is mediated through the interaction between microglia‐derived VDBP and the neuronal receptor megalin, which regulates the downstream SRC signaling pathway, leading to apoptosis, impaired synaptic function, and an excitatory/inhibitory ...
Yan Kong, Xian Zhang, Ling Li, Te Zhao, Zihan Huang, Aini Zhang, Yun Sun, Jiao Jiao, Gaojia Zhang, Mengyu Liu, Yijun Han, Linfeng Yang, Zhijun Zhang   +12 more
wiley   +1 more source

Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats

Biology of Sex Differences, 2012
Background Infectious diseases and inflammation during pregnancy increase the offspring’s risk for behavioral disorders. However, how immune stress affects neural circuitry during development is not well known.
Taylor Patrick V, Veenema Alexa H, Paul Matthew J, Bredewold Remco, Isaacs Stephanie, de Vries Geert J   +5 more
doaj   +1 more source

DHARANI: A 3D Developing Human‐Brain Atlas Resource to Advance Neuroscience Internationally Integrated Multimodal Imaging and High‐Resolution Histology of the Second Trimester

Journal of Comparative Neurology, Volume 533, Issue 2, February 2025.
ABSTRACT We introduce DHARANI, the first online platform with three‐dimensional (3D) histological reconstructions of the developing human brain from 14 to 24 gestational weeks (GW) across the five fetal brains. DHARANI features 5132 Nissl, hematoxylin and eosin stained, 20 µm coronal and sagittal sections, postmortem MRI, and a neuroanatomical atlas ...
Richa Verma, Mihail Bota, Keerthi Ram, Jaikishan Jayakumar, Rebecca Folkerth, Karthika Pandurangan, Jivitha Jyothi Ramesh, Moitrayee Majumder, Rakshika Raveendran, Reetuparna Nanda, Sivamani K, Amal Dhivahar S, Srinivasa Karthik, Ramdayalan Kumarasami, Suresh S, S. Lata, E. Harish Kumar, Rajeswaran Rangasami, Chitra Srinivasan, Jayaraman Kumutha, Sudha Vasudevan, Koushik Bhat, Chrisline Sam C, Sivathanu Neelakantan, Stephen Savoia, Partha P. Mitra, Jayaraj Joseph, Paul R. Manger, Mohanasankar Sivaprakasam   +28 more
wiley   +1 more source

Intradermal Injection of Oxytocin Aggravates Chloroquine-Induced Itch Responses via Activating the Vasopressin-1a Receptor/Nitric Oxide Pathway in Mice

Frontiers in Pharmacology, 2019
Oxytocin (OT), a hormone synthesized within the paraventricular nucleus and supraoptic nucleus of the hypothalamus, when given intracerebroventricularly, induces strong scratching behaviors.
Rulong Li, Hua Sun, Haotian Zheng, Zhihua Zong, Shengnan Li, Tingting Meng, Jing Li, Yunfang Liu, Chao Wang, Jingxin Li   +9 more
doaj   +1 more source

Light disrupts social memory via a retina-to-supraoptic nucleus circuit. [PDF]

EMBO Rep, 2023
Huang YF, Liao PY, Yu JH, Chen SK.
europepmc   +1 more source

Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus

The Journal of Physiology, 1997
In the rat, projections from the suprachiasmatic nucleus (SCN) to the supraoptic nucleus (SON) of the hypothalamus were characterized in vivo using extracellular recordings and in slice preparations using both extracellular and whole‐cell patch clamp recording. Of 117 magnocellular neurones recorded in the SON in vivo, fifteen (13%) displayed a short
L.-N. Cui, Richard E.J. Dyball, Kourosh Saeb-Parsy   +2 more
openaire   +4 more sources

Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration. [PDF]

NPJ Aging, 2023
Elsamad G, Mecawi AS, Pauža AG, Gillard B, Paterson A, Duque VJ, Šarenac O, Žigon NJ, Greenwood M, Greenwood MP, Murphy D.   +10 more
europepmc   +1 more source

RESPIRATION AND MITOCHONDRIAL CONTENT IN SINGLE NEURONS OF THE SUPRAOPTIC NUCLEUS [PDF]

, 1968
Sverker Eneström, Anders Hamberger
openalex   +1 more source

Expression of vasopressin mRNA in the hypothalamus of individuals with a diagnosis of schizophrenia

Brain and Behavior, 2019
Objective This study investigates the expression of mRNA encoding vasopressin in the hypothalamus of autopsy brains of individuals diagnosed with schizophrenia.
Johannes R. Busch, Christina Jacobsen, Niels Lynnerup, Jytte Banner, Morten Møller   +4 more
doaj   +1 more source

Na_X Channel Is a Physiological [Na⁺] Detector in Oxytocin- and Vasopressin-Releasing Magnocellular Neurosecretory Cells of the Rat Supraoptic Nucleus. [PDF]

J Neurosci, 2023
Salgado-Mozo S, Thirouin ZS, Wyrosdic JC, García-Hernández U, Bourque CW.   +4 more
europepmc   +1 more source