Results 91 to 100 of about 649,627 (304)

Dynamics of the Land–Sea Breeze System and the Surface Current Response in South-West Australia

Journal of Marine Science and Engineering, 2020
The land–sea breeze (LSB) system, driven by the thermal contrast between the land and the adjacent ocean is a widely known atmospheric phenomenon, which occurs in coastal regions globally.
Syeda Rafiq, Charitha Pattiaratchi, Ivica Janeković   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A 25-years dataset of ageostrophic, Ekman and Stokes surface currents in the Mediterranean Sea (AGESC-Med). [PDF]

Data Brief, 2023
Morales-Márquez V, Hernández-Carrasco I, Orfila A.   +2 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

High-resolution modeling of local-scale currents using machine learning and artificial intelligence: application to Santander Bay

Frontiers in Marine Science
High-resolution hydrodynamic data are essential for coastal and estuarine management. However, traditional downscaling methods based on numerical modeling remain computationally expensive, limiting their applicability for long-term hindcasts and ...
Mirko Rupani, Ana J. Abascal, Rodrigo Manzanas, Javier García-Alba, Andrés García   +4 more
doaj   +1 more source

Comparative Study on Assimilating Remote Sensing High Frequency Radar Surface Currents at an Atlantic Marine Renewable Energy Test Site

Remote Sensing, 2017
A variety of data assimilation approaches have been applied to enhance modelling capability and accuracy using observations from different sources. The algorithms have varying degrees of complexity of implementation, and they improve model results with ...
Lei Ren, Michael Hartnett
doaj   +1 more source

Topological surface currents accessed through reversible hydrogenation of the three-dimensional bulk. [PDF]

Nat Commun, 2022
Deng H, Zhao L, Park K, Yan J, Sobczak K, Lakra A, Buzi E, Krusin-Elbaum L.   +7 more
europepmc   +1 more source

Andreev bound states in high-$T_c$ superconducting junctions

, 2001
The formation of bound states at surfaces of materials with an energy gap in the bulk electron spectrum is a well known physical phenomenon. At superconductor surfaces, quasiparticles with energies inside the superconducting gap $\Delta$ may be trapped ...
Ambegokar V, Andreev A F, Andreev A F, Annett J, Artemenko S N, Ashcroft N W, Barash Y S, Beenakker C W J, de Gennes P G, Delin K A, Estève D, G Wendin, Gross R, Honerkamp C, Hussey N E, Imry Y, Kashiwaya S, Kulik I O, Melsen J A, T Löfwander, V S Shumeiko, Vollhardt D, Wolf E L, Zagoskin A M, Zagoskin M, Zavaritsky N, Zhu J X   +26 more
core   +1 more source