Results 111 to 120 of about 550,572 (306)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Effects of Twisting and Surface Finish on the Mechanical Properties of Natural Gut Harp Strings. [PDF]
Materials (Basel), 2023 Lynch-Aird N, Woodhouse J.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Surface Roughness Prediction in Grinding: a Probabilistic Approach
MATEC Web of Conferences, 2016 Surface quality of machined components is one of the most important criteria for the assessment of grinding processes. The importance of surface finish of a product depends upon its functional requirements.
Saxena Krishna Kumar +2 more
doaj +1 more source
Multiscale Modeling of a Chain Comprising Selective Laser Melting and Post-Machining toward Nanoscale Surface Finish. [PDF]
Materials (Basel), 2023 Teimouri R.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Usinagem de materiais endurecidos.
Revista Tecnologia, 2009 Turning has merged as a visible alternative to finish machining of hardened steels. It is known the surface finish and residual stresses can affect the resistance of components to failure when subjected to high cycle fatigue loads. This paper presents an
Francisco Elicivaldo Lima +1 more
doaj
Advanced Manufacturing: Polymer & Composites Science, 2018 Composite structures used as aerosurfaces in aerodynamic applications are required to have a certain surface finish quality. In manufacturing of thermoplastic composites using automated fiber placement (AFP) for aerodynamic applications, it is not only ...
F. Shadmehri +3 more
doaj +1 more source
In-Process Orbiting Laser-Assisted Technique for the Surface Finish in Material Extrusion-Based 3D Printing. [PDF]
Polymers (Basel), 2023 Han P +5 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source