Results 111 to 120 of about 50,696 (309)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Hydrophilization of rice seeds by plasma treatments – Super-hydrophilic surface finish and hydrophobic recovery [PDF]

The hydrophobic character of rice seeds protects them from quick water adsorption and, thus, premature germination. This property is, however, a drawback in modern agriculture, where rapid and uniform germination represents a high-quality trait. A method
Gupta Tondepu, Sri Amarnadh, Tonto, Teodora Chiara, Balestrazzi, Alma, Dueñas, Conrado Jr., Macovei, Anca, Primc, Gregor, Locato, Vittoria, Ogrinc, Nives, Lehocký, Marián, Lojen, Dane, Zoani, Claudia, Zaplotnik, Rok, Mozetič, Miran, Vesel, Alenka   +13 more
core   +2 more sources

Effects of Twisting and Surface Finish on the Mechanical Properties of Natural Gut Harp Strings. [PDF]

Materials (Basel), 2023
Lynch-Aird N, Woodhouse J.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Quantitative characterisation of surface finishes on stainless steel sheet using 3D surface topography analysis [PDF]

, 2006
The main aim of this project was to quantitatively characterise the developed surface topography of finishes on stainless steel sheet using three-dimensional surface analysis techniques.
Waterworth, Adelle
core  

Usinagem de materiais endurecidos.

Revista Tecnologia, 2009
Turning has merged as a visible alternative to finish machining of hardened steels. It is known the surface finish and residual stresses can affect the resistance of components to failure when subjected to high cycle fatigue loads. This paper presents an
Francisco Elicivaldo Lima, Maurício Corrêa   +1 more
doaj  

Effect of in situ treatment on the quality of flat thermoplastic composite plates made by automated fiber placement (AFP)

Advanced Manufacturing: Polymer & Composites Science, 2018
Composite structures used as aerosurfaces in aerodynamic applications are required to have a certain surface finish quality. In manufacturing of thermoplastic composites using automated fiber placement (AFP) for aerodynamic applications, it is not only ...
F. Shadmehri, S. V. Hoa, J. Fortin-Simpson, H. Ghayoor   +3 more
doaj   +1 more source

Multiscale Modeling of a Chain Comprising Selective Laser Melting and Post-Machining toward Nanoscale Surface Finish. [PDF]

Materials (Basel), 2023
Teimouri R.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source