Results 121 to 130 of about 548,019 (357)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Surface Roughness Prediction in Grinding: a Probabilistic Approach

MATEC Web of Conferences, 2016
Surface quality of machined components is one of the most important criteria for the assessment of grinding processes. The importance of surface finish of a product depends upon its functional requirements.
Saxena Krishna Kumar, Agarwal Sanjay, Das Raj   +2 more
doaj   +1 more source

Multiscale Modeling of a Chain Comprising Selective Laser Melting and Post-Machining toward Nanoscale Surface Finish. [PDF]

Materials (Basel), 2023
Teimouri R.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

In-Process Orbiting Laser-Assisted Technique for the Surface Finish in Material Extrusion-Based 3D Printing. [PDF]

Polymers (Basel), 2023
Han P, Zhang S, Yang Z, Riyad MF, Popa DO, Hsu K.   +5 more
europepmc   +1 more source

Objective surface evaluation of fiber reinforced polymer composites

, 2013
The mechanical properties of advanced composites are essential for their structural performance, but the surface finish on exterior composite panels is of critical importance for customer satisfaction.
A Bussiba, BB Hubbard, D Czarkowski, DB Percival, DE Johnson, G Landini, G Palardy, JG Daugman, K Wood, M Roberts, MH Bharati, N Hu, P Podsiadlo, PJ Schubel, R Sarathi, S Hu, S Mallat, S Pal, S Palmer, SI Chang, Stuart Palmer, T Lindblad, TH Loutas, Wayne Hall, WJ Krzanowski   +24 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Study of Evaluation of Finish Line of Die in Fixed Prosthodontic Laboratory

Update Dental College Journal
Background: The purpose of a fixed prosthodontic treatment may vary from the restoration of a single tooth to the complete rehabilitation of full occlusion.
Md Alamgir Kabir, Mohammed Mahbub Zaki, Jannatul Ferdous, Atique Mahmud, Alimul Rajii, Md Masudur Rahman, Md Mahbubur Rahman   +6 more
doaj   +1 more source

Influence of EDM Process Parameters on the Surface Finish of Alnico Alloys. [PDF]

Materials (Basel), 2022
Bańkowski D, Młynarczyk P.
europepmc   +1 more source

Some aerodynamic considerations related to wind tunnel model surface definition [PDF]

The aerodynamic considerations related to model surface definition are examined with particular emphasis in areas of fabrication tolerances, model surface finish, and orifice induced pressure errors.
Gloss, B. B.
core   +1 more source