Results 101 to 110 of about 108,558 (304)
The Astrophysical JournalOxygen-containing complex organic molecules are key precursors to biorelevant compounds fundamental for the origins of life. However, the untangling of their interstellar formation mechanisms has just scratched the surface, especially for oxygen ...
Jia Wang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The Astrophysical JournalWe computationally investigated the chemical evolution of H _2 O:O _2 ices (6:1 ratio) under irradiation by cosmic-ray analogs (0.8 MeV H ^+ ) at 9, 50, and 100 K to understand the implications the chemical evolution of O _2 -containing ices in space ...
J. R. C. Silva +3 more
doaj +1 more source
Cruise report hydro acoustic survey for blue whiting (Micromesistius poutassou) with R.V. Tridens, 17 March - 04 April 2008 [PDF]
This is the report of the Dutch part of the international North East Atlantic hydro acoustic survey for blue whiting. The survey is coordinated by ICES and has been executed annually. The purpose of the survey is to estimate the blue whiting stock of the
Armstrong, E. +6 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
The Relative Cold-trapping Likelihood of Water on Airless Rocky Bodies
The Planetary Science JournalMany planetoids are airless, but despite the lack of a collisional atmosphere, these bodies can experience volatile migration toward the polar regions via the exosphere.
T. Giang Nguyen +2 more
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Pluto and Charon: Surface Colors and Compositions - A Hypothesis [PDF]
The surface of Pluto displays an array of colors ranging from yellow to red to brown, while the surface of Charon is largely gray with a north polar zone of red color similar to regions on Pluto. Pluto's surface shows layers of intensely colored material
Cruikshank, D. P.
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source