Results 41 to 50 of about 108,558 (304)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesTrans-Neptunian objects (TNOs) exhibit a color diversity containing a wealth of clues for understanding complex compositions and the formation history of our solar system.
Chaojiang Zhang +4 more
doaj +1 more source
mBio, 2018 The discovery of integrative conjugative elements (ICEs) in wall-less mycoplasmas and the demonstration of their role in massive gene flows within and across species have shed new light on the evolution of these minimal bacteria. Of these, the ICE of the
Eric Baranowski +8 more
doaj +1 more source
Remote Sensing, 2022 As an island nation, Ireland needs to ensure effective management measures to protect marine ecosystems and their services, such as the provision of fishery resources.
Gema Casal, Clara Cordeiro, Tim McCarthy
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Investigating the Stability and Distribution of Surface Ice in Mercury’s Northernmost Craters
The Planetary Science Journal, 2023 Observations made by Earth-based radar telescopes and the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft provided compelling evidence for water ice in Mercury's polar craters.
Allison K. Glantzberg +10 more
doaj +1 more source
Color, composition, and thermal environment of Kuiper Belt object (486958) Arrokoth [PDF]
, 2020 The outer Solar System object (486958) Arrokoth (provisional designation 2014 MU₆₉) has been largely undisturbed since its formation. We study its surface composition using data collected by the New Horizons spacecraft. Methanol ice is present along with
Grundy, W. M., Keane, J. T.
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Lunar North Polar Cold Traps Based on Diurnally and Seasonally Varying Temperatures
The Planetary Science JournalLunar cold traps are defined by extremely low sublimation rates, such that water ice could have accumulated in them. Here time-averaged sublimation rates are calculated for the north polar region of the Moon based on over 14 years of Diviner surface ...
Norbert Schörghofer +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source