Results 151 to 160 of about 2,535,997 (314)

Surface Potential Modulation in Boronate-Functionalized Magnetic Nanoparticles Reveals Binding Interactions: Toward Magnetophoretic Capture/Quantitation of Sugars from Extracellular Matrix. [PDF]

Langmuir, 2023
Lyons S, Baile Pomares P, Vidal L, McGarry K, Morrin A, Brougham DF.   +5 more
europepmc   +1 more source

Distribution and Potential Ecological Risk Assessment of Copper in Surface Sediments of Southern Kaohsiung Harbor, Taiwan

, 2013
Chiu Wen Chen, Chiu‐Wen Chen, Cheng‐Di Dong   +2 more
openalex   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Molecular Electrostatic Surface Potential: A Predictive Framework for Noncovalent Interactions and Adsorption Characteristics in Molecular Entities. [PDF]

Int J Mol Sci
Varadwaj PR, Marques HM, Varadwaj A, Grabowski I, Yamashita K.   +4 more
europepmc   +1 more source

Assessing the potential of a surface water body for multiple uses. Case study: the Anambra River Basin, south-eastern Nigeria

, 2023
S. N., Magareth Kelechi Odo, E.C. Ezikanyi, Anayo Charles Iwuji, Chukwukere Austin Okezie   +4 more
openalex   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Probing nanomechanical, interfacial forces, and surface potential properties of MXene-nanocellulose composites. [PDF]

RSC Adv
Li J.
europepmc   +1 more source

Clinical Utility of Body Surface Potential Mapping in CRT Patients. [PDF]

Arrhythm Electrophysiol Rev, 2021
Sedova K, Repin K, Donin G, Dam PV, Kautzner J.   +4 more
europepmc   +1 more source

He-LiF surface potential from fast atom diffraction under grazing incidence [PDF]

, 2009
Andreas Schüller, H. Winter, M. S. Gravielle, Miguel Pruneda, J. E. Miraglia   +4 more
openalex   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source