Results 71 to 80 of about 5,084,579 (305)
Parameters Modification of Peck Formula for Surface Settlement of Shield Tunnelling in Luoyang [PDF]
Zhengzhou Daxue xuebao. Gongxue banIn order to accurately predict the surface settlement of the shield tunnel in the silty clay and sand gravel composite formation in Luoyang, a linear regression fitting method was proposed.
GAO Xinjun +3 more
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Yantu gongcheng xuebaoThe disturbance of the surrounding soil by tunnel excavation will inevitably lead to surface settlement. When calculating the surface settlement caused by tunnel excavation, various prediction methods have assumed that the tunnel convergence mode is ...
ZHOU Pengyuan 1, 2, SONG Zhanping 1, 2, 3, WANG Junbao 1, 2, ZHANG Yuwei 1, 2, 3, TIAN Xiaoxu 1, 2
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Effect of surface interactions on the settlement of particles on a sinusoidally corrugated substrate
RSC Advances, 2020 The interplay among the surface modulus, geometry, and interactions between the surface and the particle governs particle settlement on sinusoidally-corrugated substrates.
Shreya Erramilli +5 more
openaire +3 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
The effect of suction on ground surface settlement for a tunnel [PDF]
E3S Web of Conferences, 2019 This paper addresses the physical modelling of a tunnel for saturated and unsaturated sand as well as tests in dry condition. A series of tests were conducted for a 50 mm diameter tunnel buried 25 mm into a poorly graded fine sand under different normal stresses: 0.78, 1.56, 2.34 and 3.31 kPa.
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Settlement risk under gross and net settlement [PDF]
Previous comparative analyses of gross and net settlement have focused on the credit risk of the central counterparty in net settlement arrangements and on the incentives for participants to alter the risk of the portfolio under net settlement.
Charles M. Kahn +2 more
core
Frontiers in Earth ScienceThe hardening small strain (HSS) model can accurately capture the stress-related characteristics of soil during the small strain stage. This model has been widely used in calculating deformations for tunnels and excavations in sand and clay strata ...
Jingkun Pi +5 more
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Centrifuge modeling of tunneling-induced ground surface settlement in sand
Underground Space, 2019 Stress changes in the soil induced by tunnel excavation may cause excessive ground settlement. However, high-quality experimental data on ground settlement due to tunnel excavation are limited. In this study, centrifuge tests are conducted to investigate
Hu Lu, Jiangwei Shi, Yu Wang, Rong Wang
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