Results 241 to 250 of about 119,289,483 (303)

Differential immunoregulation by human surfactant protein A variants determines severity of SARS-CoV-2-induced lung disease. [PDF]

Front Immunol
Jacob IB, Lawal AO, Mahmoud SS, Kopsack EM, Reynolds ES, Meng Q, Fan H, Massa PT, Thangamani S, Jia H, Wang G.   +10 more
europepmc   +1 more source

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

Advanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva, Felipe L. Bacellar, Raquel Amaral, Louis‐Josselin Lavier‐Aydat, Luísa Cortes, Kamal Asadi, Leïla Tirichine, Paulo R. F. Rocha   +7 more
wiley   +1 more source

A rare interstitial lung disease in young adulthood due to surfactant protein C gene mutation: Two case reports with brief literature review. [PDF]

Radiol Case Rep
Sengul Y, Gosche E, Hazelton T.
europepmc   +1 more source

Surfactant protein-D is an independent predictor of all-cause mortality in men with peripheral artery disease diagnosed by population-based screening. [PDF]

Front Cardiovasc Med
Christensen KB, Obel LM, Lindholt JS, Sorensen GL.   +3 more
europepmc   +1 more source

The value of surfactant protein a in evaluating the severity and prognosis in community-acquired pneumonia patients. [PDF]

BMC Pulm Med
Deng YP, Sun J, He QY, Liu Y, Fu L, Zhao H.   +5 more
europepmc   +1 more source

A phase 1b randomized, multicenter, dose determination trial of zelpultide alfa (recombinant human surfactant protein D) in preterm neonates at high risk of developing bronchopulmonary dysplasia. [PDF]

Front Pediatr
Alonso-Ojembarrena A, Poindexter B, Aleem S, Healy H, Aguar-Carrascosa M, Moliner-Calderón E, Serrano-Martín MDM, Arroyo R, Vento M.   +8 more
europepmc   +1 more source

RETRACTION: Innate Immune Molecule Surfactant Protein D Attenuates Sepsis-Induced Acute Kidney Injury Through Modulating Apoptosis and Nfκb-Mediated Inflammation. [PDF]

Int Wound J
europepmc   +1 more source

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In defense of the lung: surfactant protein A and surfactant protein D

Current Opinion in Pharmacology, 2006
The lung is repeatedly exposed to inhaled particles and pathogens that are cleared by the actions of a multi-component innate host defense system. The pulmonary collectins--surfactant proteins A (SP-A) and D (SP-D)--play important roles in innate host defense by binding and clearing invading microbes from the lung.
Paul S, Kingma, Jeffrey A, Whitsett
openaire   +2 more sources

Pulmonary Surfactant and Drug Delivery: Focusing on the Role of Surfactant Proteins

Journal of Controlled Release, 2018
Pulmonary surfactant (PS) has been extensively studied because of its primary role in mammalian breathing. The deposition of this surface-active material at the alveolar air-water interface is essential to lower surface tension, thus avoiding alveolar collapse during expiration. In addition, PS is involved in host defense, facilitating the clearance of
Roberta Guagliardo, Stefaan C De Smedt, Koen Raemdonck   +2 more
exaly   +5 more sources