Results 281 to 290 of about 985,929 (323)

Surfactant protein A and D in the reproductive tract of stallion

Theriogenology, 2006
The presence of surface-active material in the lung alveolus has been known for several decades as being essential for normal lung function. The host defense and controlling inflammatory processes of the lung are the major functions of SP-A and SP-D.
Ata, Ayhan, Kankavi, Orhan, Ciftcioglu, M. Akif   +2 more
openaire   +4 more sources

Surfactant Protein D Deficiency

Definitions, 2020
openaire   +2 more sources

Surfactant Proteins A and D and Pulmonary Host Defense

Annual Review of Physiology, 2001
▪ Abstract  The lung collectins, SP-A and SP-D, are important components of the innate immune response to microbial challenge and participate in other aspects of immune and inflammatory regulation within the lung. Both proteins bind to surface structures expressed by a wide variety of microorganisms and have the capacity to modulate multiple leukocyte ...
E, Crouch, J R, Wright
openaire   +2 more sources

Agglutination ofPseudomonas aeruginosa by Surfactant Protein D

Pediatric Pulmonology, 2005
Surfactant protein D (SP-D) is part of the innate host defense system, and may bind and agglutinate invading microorganisms to enhance their removal. The ability of bronchoalveolar lavage (BAL) fluid to agglutinate bacteria and the relationship to its SP-D content are of interest and not yet known.
Matthias, Griese, Vitaliy, Starosta
openaire   +2 more sources

Surfactant protein D in atopic dermatitis and psoriasis

Experimental Dermatology, 2006
Abstract:  The collectin surfactant protein‐D (SP‐D) shows antimicrobial and immuno‐regulatory properties and has recently been detected in the basal layers of normal human skin. This molecule potentially plays an important role in inflammatory skin diseases and therefore SP‐D content and location was examined using immunohistochemistry on skin ...
Hohwy, Thomas, Otkjaer, Kristian, Madsen, Jens, Søerensen, Gritt, Nielsen, Ole, Vestergaard, Christian, Steiniche, Torben, Holmskov, Uffe, Lomholt, Hans   +8 more
openaire   +5 more sources

Surfactant proteins A and D in the genital tract of mares

Animal Reproduction Science, 2007
The presence of surface-active material in the lung alveolus has been known for several decades as being essential for normal lung function. Surfactant is essential for reducing the surface tension at the alveolar air-liquid interface. Pulmonary surfactant is composed of 90% lipids and 10% proteins.
Gungor, Orsan, Ata, Ayhan, Kankavi, Orhan   +2 more
openaire   +4 more sources

Immunolocalization of Surfactant Protein A and D in Sinonasal Mucosa

American Journal of Rhinology, 2006
Background Surfactant-associated proteins (SP) A and D are in the family of collectin proteins that play an integral part in the innate defense system. SP-A and SP-D expression and function are altered in a variety of inflammatory and infectious diseases of the lungs, such as asthma, allergies, and cystic fibrosis.
Bradford A, Woodworth, Deanne, Lathers, Jeffery G, Neal, Margaret, Skinner, Mary, Richardson, M Rita, Young, Rodney J, Schlosser   +6 more
openaire   +2 more sources

Surfactant Protein-D and Surfactant Inhibit Endotoxin-Induced Pulmonary Inflammation

Chest, 2007
Acute lung injury is a common cause of morbidity and mortality following pulmonary or systemic infections. Surfactant protein-D is a member of the collectin family of proteins, which play important roles in innate host defense of the lung. In this study, the effect of exogenous recombinant human SP-D (rhSP-D) on protection of the adult mouse lung from ...
Machiko, Ikegami, Elizabeth A, Scoville, Shawn, Grant, Thomas, Korfhagen, William, Brondyk, Ronald K, Scheule, Jeffrey A, Whitsett   +6 more
openaire   +2 more sources

Interactions of Surfactant Protein D with Fatty Acids

American Journal of Respiratory Cell and Molecular Biology, 2003
Abstract Surfactant Protein D (SP-D) plays important roles in antimicrobial host defense, inflammatory and immune regulation, and pulmonary surfactant homeostasis. The best-characterized endogenous ligand is phosphatidylinositol; however, this lipid interaction at least in part involves the carbohydrate moiety.
Nihal S, DeSilva, Itzhak, Ofek, Erika C, Crouch   +2 more
openaire   +2 more sources

Developmental Expression of Pulmonary Surfactant Protein D (SP-D)

American Journal of Respiratory Cell and Molecular Biology, 1991
Abstract Surfactant protein D (SP-D) is a collagenous, surfactant-associated, carbohydrate-binding protein that is synthesized by pulmonary epithelial cells. In the present studies, we examined the expression of SP-D and SP-D mRNA during late fetal (day 17, 19, 21) and early postnatal (day 5) rat lung development using immunochemical,
E, Crouch, K, Rust, W, Marienchek, D, Parghi, D, Chang, A, Persson   +5 more
openaire   +2 more sources