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Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery [PDF]

open access: yesFrontiers in Pharmacology, 2017
Surfactin, a cyclic lipopeptide biosurfactant produced by various strains of Bacillus genus, has been shown to induce cytotoxicity against many cancer types, such as Ehrlich ascites, breast and colon cancers, leukemia and hepatoma.
Yuan-Seng Wu   +12 more
doaj   +3 more sources

Improving Surfactin Production in Bacillus subtilis 168 by Metabolic Engineering

open access: yesMicroorganisms
Surfactin is widely used in the petroleum extraction, cosmetics, biopharmaceuticals and agriculture industries. It possesses antibacterial and antiviral activities and can reduce interfacial tension.
Zihao Guo   +6 more
doaj   +2 more sources

The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Surfactin is a lipoheptapeptide produced by several Bacillus species and identified for the first time in 1969. At first, the biosynthesis of this remarkable biosurfactant was described in this review.
Ariane Théatre   +16 more
doaj   +2 more sources

The use of surfactin in inhibiting Botrytis cinerea and in protecting winter jujube from the gray mold

open access: yesAMB Express, 2023
Surfactin has the potential to be used as a food preservative. However, efficiency and action mechanism in various applications need more assessments and research.
Peng Xiao   +4 more
doaj   +2 more sources

Optimizing surfactin yield in Bacillus velezensis BN to enhance biocontrol efficacy and rhizosphere colonization

open access: yesFrontiers in Microbiology
IntroductionSurfactins, a class of lipopeptide biosurfactants secreted by plant growth-promoting rhizobacteria (PGPR), have garnered significant attention due to their dual functionality in promoting plant growth and controlling plant diseases.
Tongshu Liu   +5 more
doaj   +2 more sources

Regulation mechanism and bioactivity characteristic of surfactin homologues with C14 and C15 fatty acid chains

open access: yesMicrobial Cell Factories
Background Surfactin, a green lipopeptide bio-surfactant, exhibits excellent surface, hemolytic, antibacterial, and emulsifying activities. However, a lack of clear understanding of the synthesis regulation mechanism of surfactin homologue components has
Yumeng Su   +6 more
doaj   +2 more sources

Molecular genetics of surfactin and its effects on different sub-populations of Bacillus subtilis

open access: yesBiotechnology Reports, 2021
Surfactin is a biosurfactant produced by Bacillus subtilis. The srfA operon, Sfp gene, and two quorum sensing systems are required for its production. The master regulator spo0A also plays an indispensable role in proper surfactin synthesis.
Faisal Bin Rahman   +3 more
doaj   +2 more sources

Antifungal Activity of Surfactin Against Cytospora chrysosperma [PDF]

open access: yesBiomolecules
Cytospora chrysosperma is a common opportunistically parasitic fungus that mainly infects forest trees, severely restricting the development of the fruit and forest industry.
Xinyue Wang   +6 more
doaj   +2 more sources

Mechanisms of Surfactin from Bacillus subtilis SF1 against Fusarium foetens: A Novel Pathogen Inducing Potato Wilt

open access: yesJournal of Fungi, 2023
Fusarium wilt is a severe and worldwide disease in potato cultivation. In this study, Fusarium foetens was first identified as the pathogen of potato wilt. Bacillus subtilis SF1 has the potential for controlling potato wilt induced by F.
Lin Liu   +6 more
doaj   +2 more sources

Surfactin Inhibits Osteoclast Differentiation by Negatively Regulating the Elk1-AP-1-NFATc1 Axis [PDF]

open access: yesBiomedicines
Background/Objectives: Surfactin is a biosurfactant with various biological activities, including antibacterial and anti-inflammatory properties; however, its effects on bone metabolism remain poorly understood.
Kazuki Maruyama   +9 more
doaj   +2 more sources

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