Results 41 to 50 of about 7,388 (202)

The anti-thrombotic activity of surfactins

open access: yesJournal of Veterinary Science, 2005
Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner.
Jong-hwan, Lim   +6 more
openaire   +2 more sources

Surfactin: A Quorum-Sensing Signal Molecule to Relieve CCR in Bacillus amyloliquefaciens

open access: yesFrontiers in Microbiology, 2020
Bacillus utilize preferred sugars such as glucose over other carbon sources due to carbon catabolite repression (CCR). Surfactin is a small signal molecule to regulate the quorum-sensing (QS) response such as biofilm formation and sporulation in B ...
Bing Chen   +4 more
doaj   +1 more source

Surfactin Shows Relatively Low Antimicrobial Activity against Bacillus subtilis and Other Bacterial Model Organisms in the Absence of Synergistic Metabolites

open access: yesMicroorganisms, 2022
Surfactin is described as a powerful biosurfactant and is natively produced by Bacillus subtilis in notable quantities. Among other industrially relevant characteristics, antimicrobial properties have been attributed to surfactin-producing Bacillus ...
Lars Lilge   +9 more
doaj   +1 more source

Enhancing surfactin production by using systematic CRISPRi repression to screen amino acid biosynthesis genes in Bacillus subtilis

open access: yesMicrobial Cell Factories, 2019
Background Surfactin is a cyclic lipopeptide that is of great industrial use owing to its extraordinary surfactant power and antimicrobial, antiviral, and antitumor activities.
Congya Wang   +4 more
doaj   +1 more source

Genetic engineering of the precursor supply pathway for the overproduction of the nC14-surfactin isoform with promising MEOR applications

open access: yesMicrobial Cell Factories, 2021
Background Surfactin, a representative biosurfactant of lipopeptide mainly produced by Bacillus subtilis, consists of a cyclic heptapeptide linked to a β-hydroxy fatty acid chain.
Fangxiang Hu   +4 more
doaj   +1 more source

Interaction of Surfactin with Membranes: A Computational Approach

open access: yesLangmuir, 2003
Modeling analysis was used to understand the molecular mechanisms of the biological activities of surfactin, in particular, its hemolytic activity. This study highlights the importance of the fatty acid chain hydrophobicity of the surfactin on its activities, the C15 homologue being the most active. This is related to its self-association capacity. The
Deleu, Magali   +7 more
openaire   +2 more sources

Identification and quantification of surfactin, a nonvolatile lipopeptide in Moutai liquor

open access: yesInternational Journal of Food Properties, 2020
Surfactin as a nonvolatile cyclic lipopeptide has attracted great attention over the past few decades. This work focused on identification, quantification, and tracing of surfactin in Moutai liquor by ultra-performance liquid chromatography coupled with ...
Zongxiao Chen   +6 more
doaj   +1 more source

Surfactin C inhibits platelet aggregation

open access: yesJournal of Pharmacy and Pharmacology, 2006
Abstract This study was designed to investigate the effect of surfactin C, which is derived from Bacillus subtilis, on platelet aggregation and homotypic leucocyte aggregation. Surfactin C strongly and dose-dependently inhibited platelet aggregation, which was stimulated both by thrombin (0.1 U mL−1), a potent agonist that activates the ...
Sung Dae, Kim   +9 more
openaire   +2 more sources

Characterization of Antifungal Lipopeptide Biosurfactants Produced by Marine Bacterium Bacillus sp. CS30

open access: yesMarine Drugs, 2019
This study was initiated to screen for marine bacterial agents to biocontrol Magnaporthe grisea, a serious fungal pathogen of cereal crops. A bacterial strain, isolated from the cold seep in deep sea, exhibited strong growth inhibition against M. grisea,
Shimei Wu   +4 more
doaj   +1 more source

Available strategies for improving the biosynthesis of surfactin: a review

open access: yesCritical Reviews in Biotechnology, 2022
Surfactin is an excellent biosurfactant with a wide range of application prospects in many industrial fields. However, its low productivity and high cost have largely limited its commercial applications. In this review, the pathways for surfactin synthesis in Bacillus strains are summarized and discussed.
Li, Xia, Jianping, Wen
openaire   +2 more sources

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