Results 71 to 80 of about 34,602 (289)

The comparative analysis of medical and surgical castration on rat prostate apoptosis and glandular atrophy

Urology Research and Practice, 2019
Objective: The aim of the study is to compare the effect of surgical and medical castration on prostate tissue apoptosis. Materials and methods: Rats were either surgically or medically castrated.
Fatih Osman Kurtuluş, Orhun Sinanoğlu, Zafer Tandoğdu, Pınar Tuzlalı, Adem Fazlıoğlu, Mete Çek   +5 more
doaj   +2 more sources

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

Animal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito, Talal Hassan, Antonio Marco Maisano, Stefania Bergagna, Cecilia Guasco, Barbara Miniscalco, Martina Tarantola, Elena Colombino, Claudio Caruso, Ahsan Muhammad, Silvia Mioletti, Laura Tomassone, Massimiliano Tursi, Cristina Vercelli, Giovanni Loris Alborali, Maria Teresa Capucchio   +15 more
wiley   +1 more source

Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential. [PDF]

, 2020
BackgroundMetastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes.
Cadaneanu, Radu M, Freeman, Michael R, Garraway, Isla P, Grasso, Catherine S, Hodge, Jennelle, Kim, Minhyung, Knudsen, Beatrice S, Kwan, Lorna, Lewis, Michael S, Li, Xinmin, Liu, Sandy T, Miller, Eric T, Quist, Michael J, Yoon, Junhee, You, Sungyong   +14 more
core  

Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer [PDF]

, 2019
This study identified LIMK2 kinase as a disease-specific target in castration resistant prostate cancer (CRPC) pathogenesis, which is upregulated in response to androgen deprivation therapy, the current standard of treatment for prostate cancer. Surgical
Broman, Meaghan M., Chang, Lei, Chowdhury, Dipanjan, Cresswell, Gregory, He, Yizhou J., Jacobsen, Max, McGuire, Callista, Nikhil, Kumar, Ratliff, Timothy L., Sandusky, George E., Satapathy, Shakti R., Shah, Kavita, Tandiary, Michael, Viccaro, Keith   +13 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

A comparison of generalized multinomial logit, random parameters logit, wtp-space and latent class models to studying consumers' preferences for animal welfare [PDF]

, 2016
The European societies are requiring that animals to be raised as closely as possible to their natural conditions. The growing concerns about animal welfare is resulting in continuous modifications of regulations and policies that led to ban of a number ...
Borrisser-Pairó,, Francesc, Gil Roig, José María, Kallas, Zein, Martínez, Beatriz, Olivar, Maria Angels, Panella-Riera, Nuria, Vieira, Ceferina   +6 more
core  

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Spartan Daily, April 11, 1984 [PDF]

, 1984
Volume 82, Issue 51https://scholarworks.sjsu.edu/spartandaily/7169/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Evaluation of chemical castration with calcium chloride versus surgical castration in donkeys: testosterone as an endpoint marker [PDF]

BMC Veterinary Research, 2016
For the last few years, researchers have been interested in developing a method for chemical sterilization which may be a better alternative to surgical castration. An ideal chemical sterilant would be one that effectively arrests spermatogenesis and androgenesis as well as libido with absence of toxic or other side effects. Calcium chloride in various
Ibrahim, Ahmed, Ali, Magda M., Abou-Khalil, Nasser S., Ali, Marwa F.   +3 more
openaire   +2 more sources