Results 51 to 60 of about 60,125 (341)
Novel Endovascular Interventional Surgical Robotic System Based on Biomimetic Manipulation
Endovascular therapy has emerged as a crucial therapeutic method for treating vascular diseases. Endovascular surgical robots have been used to enhance endovascular therapy.
Chao Song +6 more
doaj +1 more source
Endovascular interventions usually require meticulous handling of surgical instruments and constant monitoring of the operating room workspace. To address these challenges, robotic- assisted technologies and tracking techniques are increasingly being developed.
Heunis, Christoff M. +3 more
openaire +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Towards automated visual flexible endoscope navigation [PDF]
Background:\ud The design of flexible endoscopes has not changed significantly in the past 50 years. A trend is observed towards a wider application of flexible endoscopes with an increasing role in complex intraluminal therapeutic procedures.
Broeders, I.A.M.J. +2 more
core +3 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Medical robots improve medical efficiency and reduce patients’ suffering that owns social significance and scientific research value.Focusing on the difficulties of medical robots, we propose the concept of parallel medical robotics based on the ACP (artificial societies, computational experiments, parallel execution)-based parallel system method ...
Tianxiang BAI +4 more
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Monolithic Electrostatic–Hydraulic Coupled Suction Pad
Suction cups are one of the most widely adopted switchable adhesive techniques and play a crucial role in manufacturing and robotics. However, conventional negative pressure sources (e.g., diaphragm vacuum pumps) suffer from poor scalability from meso ...
Chongjing Cao, Lei Wang, Xing Gao
doaj +1 more source
Soft Robotic Deployable Origami Actuators for Neurosurgical Brain Retraction
Metallic tools such as graspers, forceps, spatulas, and clamps have been used in proximity to delicate neurological tissue and the risk of damage to this tissue is a primary concern for neurosurgeons.
Tomas Amadeo +6 more
doaj +1 more source

