Results 61 to 70 of about 21,824 (301)

Soft Robotic Deployable Origami Actuators for Neurosurgical Brain Retraction

Frontiers in Robotics and AI, 2022
Metallic tools such as graspers, forceps, spatulas, and clamps have been used in proximity to delicate neurological tissue and the risk of damage to this tissue is a primary concern for neurosurgeons.
Tomas Amadeo, Daniel Van Lewen, Taylor Janke, Tommaso Ranzani, Anand Devaiah, Urvashi Upadhyay, Sheila Russo   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Performance-Driven Tasks with Adaptive Difficulty for Enhanced Surgical Robotics Training [PDF]

Surgical robotics training most often occurs through standardized curricula and exercises that lack customization and do not adapt to the different levels of proficiency that trainees often present. This work proposes a Virtual Reality (VR) simulator for
Rota, Alberto, De Momi, Elena, Sun, Xianyi Federica   +2 more
core   +1 more source

Magnetic localization and manipulation of locking synchronous motors

Communications Engineering
Three-dimensional (3D) localization of magneto-surgical devices is essential for safe and efficient navigation. However, existing magnetic localization methods either limit device miniaturization due to internal sensors or require additional excitation ...
Michiel Richter, Lukas Masjosthusmann, Pavlo Makushko, Venkatasubramanian Kalpathy Venkiteswaran, Denys Makarov, Sarthak Misra   +5 more
doaj   +1 more source

A wrist for needle-sized surgical robots [PDF]

2015 IEEE International Conference on Robotics and Automation (ICRA), 2015
The needle-sized surgical tools used in arthroscopy, otolaryngology, and other surgical fields could become even more valuable to surgeons if endowed with the ability to navigate around sharp corners to manipulate or visualize tissue. We present a needle-sized wrist design that grants this ability.
Peter A. York, Philip J. Swaney, Hunter B. Gilbert, Robert J. Webster III   +3 more
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Application of Artificial Intelligence in Surgical Robotics

Zhongguo yiliao qixie zazhi
Surgical robots represent one of the important diagnostic and treatment methods in the field of surgery. In recent years, artificial intelligence (AI) has been increasingly used in the field of surgical medicine, especially in the field of robotic ...
Linghan ZHANG, Yuan LIN
doaj   +1 more source

Bi-directional transportation of micro-agents induced by symmetry-broken acoustic streaming

AIP Advances, 2019
We show that vibrating protrusions inside a microchannel are capable of steering fluid away from their relative orientation. This phenomenon is brought forth by symmetry-broken design of these protrusions.
Sumit Mohanty, Ugo Siciliani de Cumis, Miguel Solsona, Sarthak Misra   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Deep Reinforcement Learning in Surgical Robotics: Enhancing the Automation Level

, 2023
Surgical robotics is a rapidly evolving field that is transforming the landscape of surgeries. Surgical robots have been shown to enhance precision, minimize invasiveness, and alleviate surgeon fatigue. One promising area of research in surgical robotics
Qian, Cheng, Ren, Hongliang
core