Results 31 to 40 of about 1,309,239 (247)

The Next-Generation of Surgical Robotics

, 2017
The chronicle of surgical robots is short but remarkable. Within 20 years since the regulatory approval of the first surgical robot, more than 3,000 units were installed worldwide, and more than half a million robotic surgical procedures were carried out
Peng, J, Wang, Z, Liu, S, Chen, MZ
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Untethered soft magnetic pump for microfluidics-based Marangoni surfer

Scientific Reports
Microfluidics has enabled the miniaturization of fluidic systems for various biomedical and industrial applications, including small-scale robotic propulsion.
Yu-Hsiang Lin, Franco N. Piñan Basualdo, Venkatasubramanian Kalpathy Venkiteswaran, Sarthak Misra   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Inductively triggered capsule robot for needle-based drug delivery

npj Robotics
Existing capsule robots designed to deliver drugs typically release them into the gastrointestinal lumen, where transport into the tissue depends on passive diffusion across physiological barriers such as the epithelial layer.
Lukas Masjosthusmann, Sarthak Misra
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

NeuRehab: a reinforcement learning and spiking neural network-based rehab automation framework

Neuromorphic Computing and Engineering
Recent advancements in robotic rehabilitation therapy have provided modular exercise systems for post-stroke muscle recovery with basic control schemes. But these systems struggle to adapt to patients’ complex and ever-changing behaviour, and to operate ...
Phani Pavan Kambhampati, Chainesh Gautam, Jagan P, Madhav Rao   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Uptake and accessibility of surgical robotics in England [PDF]

, 2020
Background The distribution, utilisation and accessibility of surgical robotics in England is unknown. Methods A nationwide Freedom of Information (FOI) request was sent to all acute National Health Service (NHS) trusts.
Clarke, Jonathan, Lam, Kyle, Purkayastha, Sanjay, Sanjay Purkayastha, James M. Kinross, Kyle Lam, Kinross, James M, Jonathan Clarke   +7 more
core   +1 more source

Robot-assisted investigation of sensorimotor control in Parkinson's disease

Scientific Reports, 2023
Sensorimotor control (SMC) is a complex function that involves sensory, cognitive, and motor systems working together to plan, update and execute voluntary movements.
Yokhesh K. Tamilselvam, Mandar Jog, Rajni V. Patel   +2 more
doaj   +1 more source