Results 31 to 40 of about 807,388 (293)

Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe neuroprotective effect of remote ischemic preconditioning (RIPC) in patients undergoing elective cardiopulmonary bypass (CPB)-assisted coronary artery bypass graft (CABG) or valvular cardiac surgery remains unclear.MethodsA randomized ...
Shouqiang Zhu, Ziyu Zheng, Wenying Lv, Pengrong Ouyang, Jiange Han, Jiaqiang Zhang, Hailong Dong, Chong Lei   +7 more
doaj   +1 more source

Evaluating Hemagglutination Inhibition Antibody Titers as a Correlate of Protection for Influenza: A Sensitivity Analysis Based on Information Theory and Causal Inference

Journal of Global Infectious Diseases
Introduction: Identifying hemagglutination inhibition (HI) antibody titers as a key immune correlate of protection (CoP) is crucial for developing, licensing, and monitoring the ongoing effectiveness of new influenza vaccines.
Fenny Ong, Geert Molenberghs, Andrea Callegaro, Wim Van Der Elst, Geert Verbeke, Florian Stijven, Ingrid Van Keilegom, Ariel Alonso Abad   +7 more
doaj   +1 more source

Biomarkers, Putative Surrogates, Surrogates, and Decision Making [PDF]

Circulation: Cardiovascular Imaging, 2013
The development of new therapies is slow, expensive, and frustrating. The failure rate for new molecular entities exceeds 90%, and total research and development costs per successful new molecular entity are currently estimated to be nearly $2 billion.1 Consternation about the complexity of therapeutic development recently prompted a major report by ...
openaire   +2 more sources

Fast prediction and evaluation of gravitational waveforms using surrogate models [PDF]

, 2013
[Abridged] We propose a solution to the problem of quickly and accurately predicting gravitational waveforms within any given physical model. The method is relevant for both real-time applications and in more traditional scenarios where the generation of
Field, Scott E., Galley, Chad R., Hesthaven, Jan S., Kaye, Jason, Tiglio, Manuel   +4 more
core   +6 more sources

A dynamical model of surrogate reactions

, 2010
A new dynamical model is developed to describe the whole process of surrogate reactions; transfer of several nucleons at an initial stage, thermal equilibration of residues leading to washing out of shell effects and decay of populated compound nuclei ...
A. N. Ignatyuk, B. E. J. Pagel, D. Arnett, H. C. Britt, J. D. Cramer, K. Nishio, N. Carjan, P. Fröbrich, R. Bass, S. Chiba, T. Asano, W. U. Schröder, Y. Aritomo   +12 more
core   +1 more source

Versatile surrogate models for IC buffers [PDF]

, 2012
In previous papers [1,2] the authors have investigated the use of Volterra series in the identification of IC buffer macro-models. While the approach benefited from some of the inherent qualities of Volterra series it preserved the two-state paradigm of ...
Canavero, Flavio, Cloastre, P., Diouf, C., Stievano, Igor Simone, Tanguy, N., Telescu, M.   +5 more
core   +3 more sources

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez, Jill O. Robinson, Wendy A. Allen‐Rhoades, Hadley S. Smith, Isabel Canfield, Rebecca L. Hsu, Sarah R. Scollon, Lauren R. Desrosiers‐Battu, Nicole M. Schneider, Frank Y. Lin, Donald Williams Parsons, Sharon E. Plon, Mary A. Majumder, Janet Malek, Amy L. McGuire   +14 more
wiley   +1 more source

On Machine-Learning-Driven Surrogates for Sound Transmission Loss Simulations

Applied Sciences, 2022
Surrogate models are data-based approximations of computationally expensive simulations that enable efficient exploration of the model’s design space and informed decision making in many physical domains.
Barbara Zaparoli Cunha, Abdel-Malek Zine, Mohamed Ichchou, Christophe Droz, Stéphane Foulard   +4 more
doaj   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source