Results 211 to 220 of about 510,312 (368)

Surrogate endpoint metaregression: useful statistics for regulators and trialists. [PDF]

J Clin Epidemiol
Baker SG, Lassere MND, Lo WP.
europepmc   +1 more source

Progression-free survival as surrogate endpoint of overall survival in esophageal squamous cell carcinoma: a real-world data and literature-based analysis. [PDF]

Ther Adv Med Oncol, 2022
Han W, Wang L, Li C, Chen J, Zhang W, Wang X, Pang Q, Zhao Y, Sun X, Zhang K, Li G, Li L, Qiao X, Liu M, Wang Y, Deng L, Wang W, Bi N, Zhang T, Deng W, Ni W, Chang X, Zhou Z, Liang J, Feng Q, Wang L, Chen D, Lv J, Zhu S, Han C, Xiao Z.   +30 more
europepmc   +1 more source

Microstructural Evolution and Mechanical Performance of Plasma‐Assisted Hybrid Friction Stir Welded Dissimilar Aluminum–Copper Joints

Advanced Engineering Materials, EarlyView.
Plasma‐assisted hybrid friction stir welding of dissimilar AlCu joints employs localized plasma preheating to balance heat input and enhance plastic flow. The optimized process reduces axial force by up to 35%, refines the microstructure, and achieves ≈96% joint efficiency.
Deepak Kumar Yaduwanshi, Pankaj Shrivastava, Ganesh Chouhan, Velaphi Msomi   +3 more
wiley   +1 more source

A maximum entropy approach for the evaluation of surrogate endpoints based on causal inference

, 2018
Ariel Alonso, Wim Van der Elst, Geert Molenberghs   +2 more
openalex   +2 more sources

Proposed study designs for approval based on a surrogate endpoint and a post-marketing confirmatory study under FDA's accelerated approval regulations for disease modifying osteoarthritis drugs.

Osteoarthritis and Cartilage, 2019
V. Kraus, L. Simon, J. Katz, T. Neogi, D. Hunter, A. Guermazi, M. Karsdal   +6 more
semanticscholar   +1 more source

Can Ti‐Based MXenes Serve as Solid Lubricants for Brake Applications? A Tribological Study

Advanced Engineering Materials, EarlyView.
This study explores the first implementation of Ti‐based MXenes materials in brake pad friction composite material. The resulting composite material exhibits a 48% reduction in the wear rate; alongside significant improvements are observed for thermal and mechanical properties.
Eslam Mahmoud, Jakob Gruber, Hakan Göçerler, Pierluigi Bilotto, Christian Gierl‐Mayer, Elham Loni, Michael Naguib, Carsten Gachot   +7 more
wiley   +1 more source

Cancer Drugs Approved Based on Surrogate Endpoint: A Retrospective Observational Study in the United States and China. [PDF]

Cancer Med
Zhu T, Zhong J, Huang Y.
europepmc   +1 more source

Use of copula to model within-study association in bivariate meta-analysis of binomial data at the aggregate level: A Bayesian approach and application to surrogate endpoint evaluation. [PDF]

Stat Med, 2022
Papanikos T, Thompson JR, Abrams KR, Bujkiewicz S.   +3 more
europepmc   +1 more source

Design and Prototyping of Topology‐Optimized, Additively Manufactured Lightweight Components for Space Robotic Systems: A Case Study

Advanced Engineering Materials, EarlyView.
The results demonstrate a simulation‐driven workflow that applies LSB topology optimization with additive manufacturing constraints to mission‐specific load cases, integrating European Cooperation for Space Standardization compliant verification and manufacturability to develop structurally efficient rover suspension components.
Stelios K. Georgantzinos, Grigorios Kostopoulos, Eleni Papadopoulou, Stefanos Voulgaris, Alexandra Tseni, Panteleimon Bakalis, Maria N. Gkara, Chara Ch. Mitropoulou, Georgios Kazakis, Alin Munteanu, Jeremi Gancet, Nikos D. Lagaros   +11 more
wiley   +1 more source

Meta-Analysis of Recurrence-Free Survival or Disease-Free Survival as a Potential Surrogate Endpoint for Overall Survival in Esophageal Cancer Trials. [PDF]

Cancer Rep (Hoboken)
Anyaduba UL, Orababa OQ, Faye Z, Rashid N, Shafrin J, Reardon G.   +5 more
europepmc   +1 more source