Results 221 to 230 of about 82,696 (289)

Unlock the Walnut: How a Pectin‐Rich Suture Tissue and Moisture‐Driven Crack Formation Induce Shell Splitting and Facilitate Seed Germination

Advanced Functional Materials, EarlyView.
Walnut seeds are enclosed in a remarkably strong shell made of sclerenchyma, separated by a pectin‐rich suture tissue. Different cell shapes and chemical composition of this tissue point to an opening mechanism, which is triggered by cyclic humidity changes.
Sebastian J. Antreich, Nannan Xiao, Martin Felhofer, Notburga Gierlinger   +3 more
wiley   +1 more source

Neoadjuvant immunochemotherapy for locally advanced esophageal squamous cell carcinoma in real-world practice: an analysis of the clinical outcomes and long-term survival, and the feasibility of using major pathological response as a surrogate endpoint. [PDF]

Eur J Med Res
Liu J, Wu Z, Zhou S, Lv W, Wang Y, Xia P, Zhu L, Hu J.   +7 more
europepmc   +1 more source

Modeling and the use of surrogate endpoints: Is this a valid approach? [PDF]

Uri Ladabaum, Luuk A van Duuren, Elizabeth Half, Zohar Levi, Barbara Silverman, Iris Lansdorp‐Vogelaar   +5 more
openalex   +1 more source

Progression-free survival as a surrogate endpoint in advanced neuroendocrine neoplasms [PDF]

, 2017
Hiroshi Imaoka, Mitsuhito Sasaki, Hideaki Takahashi, Yusuke Hashimoto, Izumi Ohno, Shuichi Mitsunaga, Kazuo Watanabe, Kumiko Umemoto, Gen Kimura, Yuko Suzuki, Masafumi Ikeda   +10 more
openalex   +1 more source

Cryo‐EM of Rationally Designed Photosystem I Nanoassembly on Graphene Validates Orientation‐Driven Enhancement of Photocatalytic Performance

Advanced Functional Materials, EarlyView.
The first cryo‐EM visualization and quantification of oriented Photosystem I (PSI) on single‐layer graphene is reported. Domain‐specific covalent anchoring of PSI, with the reducing side of the biophotocatalyst toward graphene, promotes three‐fold higher anodic photocurrent generation compared to a randomly physisorbed counterpart. This approach allows
Miriam Izzo, Margot Jacquet, Tomasz Góral, Marcin Strawski, Takayuki Fujiwara, Shin‐ya Miyagishima, Joanna Kargul   +6 more
wiley   +1 more source

Progression-free survival as a surrogate endpoint for overall survival in patients with relapsed or refractory multiple myeloma. [PDF]

BMC Cancer
Dimopoulos M, Sonneveld P, Manier S, Lam A, Roccia T, Schecter JM, Cost P, Pacaud L, Poirier A, Tremblay G, Lan T, Valluri S, Kumar S.   +12 more
europepmc   +1 more source

Validation of Estimated Glomerular Filtration Slope and Proteinuria Reduction as Surrogate Endpoints in IgA Nephropathy: A post-hoc Analysis from the J-IGACS [PDF]

Takaya Sasaki, Nobuo Tsuboi, Kentaro Koike, Hiroyuki Ueda, Masahiro Okabe, Shinya Yokote, Akihiro Shimizu, Keita Hirano, Tetsuya Kawamura, Takashi Yokoo, Yusuke Suzuki   +10 more
openalex   +1 more source

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Steep‐Switching Memory FET for Noise‐Resistant Reservoir Computing System

Advanced Functional Materials, EarlyView.
We demonstrate the steep‐switching memory FET with CuInP2S6/h‐BN/α‐In2Se3 heterostructure for application in noise‐resistant reservoir computing systems. The proposed device achieves steep switching characteristics (SSPGM = 19 mV/dec and SSERS = 23 mV/dec) through stabilization between CuInP2S6 and h‐BN.
Seongkweon Kang, Jaerok Kim, Sang‐Min Lee, Sungpyo Baek, Saeroonter Oh, Yoonmyung Lee, Sungjoo Lee   +6 more
wiley   +1 more source

End points for sickle cell disease clinical trials: Patient-reported outcomes, pain, and the brain [PDF]

, 2019
al., et, Farrell, Ann T., King, Allison A.   +2 more
core   +1 more source