Results 31 to 40 of about 82,696 (289)
The 6-minute walk test and other endpoints in Duchenne muscular dystrophy: longitudinal natural history observations over 48 weeks from a multicenter study. [PDF]
, 2013 IntroductionDuchenne muscular dystrophy (DMD) subjects ≥5 years with nonsense mutations were followed for 48 weeks in a multicenter, randomized, double-blind, placebo-controlled trial of ataluren.Abresch, R Ted, Barth, Jay, Eagle, Michelle, Elfring, Gary, Florence, Julaine M, Gappmaier, Eduard, Glanzman, Allan M, Henricson, Erik K, McDonald, Craig M, Peltz, Stuart, PTC124-GD-007-DMD Study Group, Reha, Allen, Spiegel, Robert +12 morecore +2 more sourcesAn Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics [PDF]
, 2018 For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types.A. Abeshouse, A. Ally, A. Antenucci, A. Arnaout, A. Berchuck, A. Bergeron, A. Bossler, A. Boussioutas, A. Breggia, A. Burnette, A. Chen, A. Clipca, A. Davis, A. De Rienzo, A. De Rose, A. Fehrenbach, A. Gillis, A. Gimenez-Roqueplo, A. Gopalan, A. Haddad, A. Hartmann, A. Jimeno, A. Kastl, A. Kendler, A. Kibel, A. Korkut, A. Longatto-Filho, A. Luna, A. Malykh, A. Mariamidze, A. Mes-Masson, A. Noss, A. Ochoa, A. Perin, A. Piché, A. Pickens, A. Rao, A. Sankarankuty, A. Secord, A. Sepulveda, A. Shabunin, A. Sharp, A. Sood, A. Spillane, A. Tam, A. Tischler, A. Tsao, A. Unterberg, A. Vicha, A. von Deimling, A.C. Berger, A.C. de Carvalho, A.D. Cherniack, A.D. Cherniack, A.E. Sloan, A.G. Robertson, A.H. Bryce, A.H. Perou, A.J. Kovatich, A.J. Kovatich, A.J. Lazar, A.J. Lazar, A.J. Mungall, A.K. Godwin, A.L. Carvalho, A.L. Guillermo, A.M. Angulo Gonzalez, A.M. Hegde, A.P. Hoyle, A.R. Metwalli, A.V. Lee, B. Bernard, B. Campos, B. Czerniak, B. Deyarmin, B. Drake, B. Esmaeli, B. Hermes, B. Hernandez, B. Kohl, B. Kumar, B. Pollo, B. Rabeno, B. Robinson, B. Singh, B. Tê, B. Van Tine, B. Wullich, B.D. Phu, B.E. Gross, B.M. Broom, B.P. O’, B.S. Taylor, B.Y. Karlan, C. Adebamowo, C. Andry, C. Behrens, C. Benz, C. Bifulco, C. Bradford, C. Brewer, C. Calatozzolo, C. Carter, C. Chen, C. Cibulskis, C. Fan, C. Farver, C. Feltmate, C. Goparaju, C. Guo, C. Herold-Mende, C. Hovens, C. Jungk, C. Kandoth, C. Larson, C. Logothetis, C. Mcpherson, C. Mirsaidi, C. Moran, C. Morrison, C. Moser, C. Sander, C. Scapulatempo-Neto, C. Schilero, C. Shelton, C. Shipman, C. Stoehr, C. Yau, C.A. Miller, C.C. Benz, C.C. Fronick, C.D. Jones, C.D. Shriver, C.D. Shriver, C.D. Vocke, C.H. Hagedorn, C.J. Creighton, C.K. Wong, C.M. Cebulla, C.M. Hutter, C.M. Perou, C.N. Landen, C.P. Raut, C.S. Shelley, C.W. Seder, D. Alvaro, D. Aziz, D. Beer, D. Bell, D. Bigner, D. Brooks, D. Chakravarty, D. Chesla, D. Crain, D. Cramer, D. Hoon, D. Huntsman, D. Lee, D. Mallery, D. Morton, D. Murawa, D. Muzny, D. Nagorney, D. O’, D. Raymond, D. Rice, D. Schadendorf, D. Tan, D. Tcaciuc, D. Tirapelli, D. Voet, D.A. Levine, D.A. Levine, D.A. Wheeler, D.I. Heiman, D.J. Brat, D.J. Van Den Berg, D.J. Weisenberger, D.M. Rassl, D.M. Shin, D.M. Wolf, D.N. Hayes, D.O. Vidal, D.T. Maglinte, E. Baudin, E. Campo, E. Castle, E. Chuah, E. Curley, E. Gaudio, E. Giné, E. Kebebew, E. Korpershoek, E. Lipp, E. Reznik, E. Shinbro, E. Swisher, E. Thompson, E. Zmuda, E.C. Zwarthoff, E.G. Van Meir, E.L. Appelbaum, E.M. Godwin, E.M. Mora Pinero, E.R. Duffy, E.R. Mardis, F. Beuschlein, F. Brimo, F. Carey, F. Cheng, F. Dimeco, F. Facciolo, F. Giuliante, F. Khuri, F. Meric-Bernstam, F. Moiseenko, F. Que, F. Saad, F. Sanchez-Vega, F. Valdivieso, F. Williams, F. Zhao, G. Barnett, G. Bubley, G. Carlos, G. Carpino, G. Finocchiaro, G. Getz, G. Gorincioi, G. Grazi, G. Long, G. Manikhas, G. Mann, G. Mckercher, G. Petersen, G. Saksena, G. Sauter, G. Setdikova, G. Sica, G. Thomas, G. Wolf, G.B. Mills, G.F. Gao, H. Al-Ahmadie, H. Colman, H. Dinh, H. Doddapaneni, H. Fan, H. Gabra, H. Gavin, H. Hai, H. Hai, H. Hibshoosh, H. Huland, H. Jianhong, H. Juhl, H. Kakavand, H. Liang, H. Noushmehr, H. Pass, H. Sekhon, H. Shen, H. Stoop, H. Taubert, H. Thai, H. Timmers, H. Yang, H. Zaren, H. Zhang, H. Zhang, H. Zhang, H.C.S. Silveira, H.G. Rosenthal, H.J. Sofia, H.K. Schmidt, I. Alexopoulou, I. Caraman, I. Chemencedji, I. de Bruijn, I. Felau, I. Forgie, I. Shmulevich, I. Stancul, I. Wistuba, I. Yang, J. Armenia, J. Bartlett, J. Bennett, J. Bondaruk, J. Bowen, J. Carlotti, J. Catto, J. Chabot, J. Cheville, J. Cho, J. Creaney, J. Dipersio, J. Drummond, J. Eckman, J. Engel, J. Eschbacher, J. Fujimoto, J. Fulop, J. Galbraith, J. Gao, J. Gardner, J. Gershenwald, J. Harr, J. Henderson, J. Hess, J. Hilty, J. Houck, J. Kim, J. Kocher, J. Lang, J. Liu, J. Liu, J. Luketich, J. Marks, J. Martin, J. Melamed, J. Miller, J. Moyer, J. Myers, J. Parfitt, J. Park, J. Paulauskis, J. Phillips, J. Powers, J. Roach, J. Santibanez, J. Shih, J. Simko, J. Slotta-Huspenina, J. Smith, J. Stretch, J. Thompson, J. Waldmann, J. Walker, J. Wang, J. Wang, J. Wilmott, J. Zhang, J. Zhenlin, J.(. Zhang, J.A. Ajani, J.A. Borgia, J.A. Copland, J.A. Demchok, J.A. Hooke, J.A. Martignetti, J.B. Elder, J.C. Zenklusen, J.D. Yang, J.E. Schein, J.H. Fregnani, J.I. Lee, J.J. Olson, J.L. Fantacone-Campbell, J.M. Chan, J.M. Gastier-Foster, J.M. Stuart, J.N. Weinstein, J.S. Barnholtz-Sloan, J.S. Dos Santos, J.S. Parker, J.T. Auman, J.V. Simons, K. Agnew, K. Ahn, K. Becker, K. Birsoy, K. Chang, K. Chung, K. Covington, K. Delman, K. Devine, K. Evason, K. Janssen, K. Junker, K. Kasaian, K. Kopp, K. Lau, K. Lee, K. Leinonen, K. Magliocca, K. Moore, K. Moxley, K. Mungall, K. Pacak, K. Rai, K. Roggin, K. Senecal, K. Shannon, K. Shimmel, K. Smith-McCune, K. Smolenski, K. Tse, K. Tucker, K.A. Hoadley, K.A. Hoadley, K.C. Sexton, K.E. van Kessel, K.J. Kang, K.M. Fong, K.M. Leraas, L. Cope, L. Cuppini, L. Danilova, L. Desjardins, L. Ding, L. Haydu, L. Jacobus, L. Jun, L. Konnor, L. Kvecher, L. Lacombe, L. Landrum, L. Lewis, L. Lolla, L. Looijenga, L. Mattei, L. Omberg, L. Omberg, L. Peterson, L. Ramondetta, L. Roberts, L. Rozek, L. Scarpace, L. Schoenfield, L. Wang, L. Wei, L. Wise, L. Xuan, L. Yang, L. Yiling, L. Zhang, L.A. Donehower, L.A. Fulton, L.A. Zach, L.E. Mose, L.M. Poisson, L.S. Schmidt, M. Albert, M. Aymerich, M. Bailey, M. Balasundaram, M. Behera, M. Bellair, M. Birrer, M. Borad, M. Carney, M. Cernat, M. Couce, M. Deqin, M. Dinkin, M. Dubina, M. Farnell, M. Fassnacht, M. Feldman, M. Gerken, M. Goodman, M. Graefen, M. Iacocca, M. Ittmann, M. Kasapi, M. Kendrick, M. Knudson, M. Ladanyi, M. Latour, M. Mannelli, M. Marino, M. Mayo, M. Mcgraw, M. Meyerson, M. Milhem, M. Miller, M. Moncrieff, M. Morgan, M. Muto, M. Nelson, M. Peto, M. Pirtac, M. Pool, M. Prados, M. Prince, M. Quinn, M. Quintero-Aguilo, M. Rivera, M. Ryan, M. Schiffman, M. Sherman, M. Sheth, M. Stanton, M. Stern, M. Synott, M. Tavobilov, M. Torbenson, M. Wang, M. Wiznerowicz, M. Yussanne, M.A. Marra, M.A. Rubin, M.C. Bragazzi, M.D. Mclellan, M.D. Wilkerson, M.G. Cordes, M.G. Nissan, M.G. Soloway, M.H. Abdel-Rahman, M.H. Kucherlapati, M.J. Liptay, M.L. Anderson, M.L. Ferguson, M.S. Bootwalla, M.S. Lawrence, M.S. Noble, N. Botnariuc, N. Chambwe, N. Corcoran, N. Dhalla, N. Gehlenborg, N. Giama, N. Girard, N. Hayward, N. Horowitz, N. Kwok-Shing, N. Schultz, N. Thiessen, N. Van Bang, N. Wentzensen, N.A. Pennell, N.C. Ramirez, N.D. Aredes, N.L. Lehman, N.P. Hung, N.V. Tien, O. Bathe, O. Mariani, O. Olabode, O. Paklina, O. Potapova, O. Voronina, P. Anur, P. Disaia, P. Drwiega, P. Glenn, P. Hansen, P. Hersey, P. Lin, P. Lohavanichbutr, P. Nair, P. Nguyen, P. Sipahimalani, P. Spellman, P. Swanson, P. Tamboli, P. Tennstedt, P. Troncoso, P. Wakely, P. Westervelt, P. Yena, P.A. Mieczkowski, P.A. Pinto, P.D. Castro, P.H. Lai, P.R. Carroll, P.R. Dottino, P.T. Hanh, P.W. Laird, Q. Sun, Q.T. Ostrom, R. Akbani, R. Berkowitz, R. Beroukhim, R. Bowlby, R. Bowman, R. Broaddus, R. Bueno, R. Carlsen, R. de Krijger, R. Dhanasekaran, R. Dhir, R. Duell, R. Ghossein, R. Glenn, R. Govindan, R. Holt, R. Kefford, R. Kemp, R. Korst, R. Kramer, R. Kundra, R. Lechan, R. Madan, R. Mandt, R. Mannel, R. Mclendon, R. Merola, R. Naresh, R. Penny, R. Pilarski, R. Postier, R. Saw, R. Scolyer, R. Sheridan, R. Sigmund, R. Simon, R. Singh, R. Smallridge, R. Steele, R. Stoehr, R. Tamakawa, R. Tarnuzzer, R. Thorp, R. Warnick, R. Worrell, R. Zuna, R.A. Gibbs, R.A. Moore, R.C. Rintoul, R.H. Thompson, R.J. Mural, R.K. Kelley, R.K. Wilson, R.M. Reis, R.S. Fulton, R.S. Kanchi, R.S. Kucherlapati, S. Balu, S. Baylin, S. Bell, S. Chevalier, S. Chudamani, S. Cottingham, S. Cuzzubbo, S. Doruc, S. Force, S. Frazer, S. Gilbert, S. Heath, S. Kalkanis, S. Kendall, S. Lee, S. Ling, S. Maithel, S. Mccall, S. Meier, S. Meng, S. Morris, S. Mura, S. Porten, S. Ramalingam, S. Reynolds, S. Roman-Roman, S. Sadeghi, S. Sifri, S. Signoretti, S. Singer, S. Somiari, S. Stepa, S. Tao, S. Vandenberg, S. Wach, S.B. Gabriel, S.E. Schumacher, S.J. Caesar-Johnson, S.J.M. Jones, S.L. Asa, S.M. Phillips, S.M. Staugaitis, S.N. Adebamowo, S.O. Sumer, S.R. Jefferys, T. Akeredolu, T. Bocklage, T. Bodenheimer, T. Broudy, T. Carey, T. Costello, T. Defreitas, T. Flotte, T. Giordano, T. Hinoue, T. Knijnenburg, T. Knutson, T. Ley, T. Lichtenberg, T. Mikkelsen, T. Naska, T. Owonikoko, T. Patel, T. Pihl, T. Schlomm, T. Shelton, T. Skelly, T. Smyrk, T. Thompson, T. Wang, T. Wong, T. Zelinka, T.A. Chan, T.M. Lichtenberg, U. Veluvolu, V. Cardinale, V. Chandan, V. Dhankani, V. Jakrot, V. Korchina, V. Lyadov, V. Reuter, V. Thorsson, V. Thorsson, W. Barrett, W. Eijckenboom, W. Hale, W. Kycler, W. Liu, W. Oosterhuis, W. Urba, W. Ye, W. Zhang, W. Zhou, W.E. Grizzle, W.G. Richards, W.J. Edenfield, W.K. Chatila, W.K. Rathmell, W.M. Linehan, X. Liu, X. Liu, X. Sastre, Y. Han, Y. Liu, Y. Shi, Y. Sun, Y. Tang, Y. Wan, Y. Wolinsky, Z. Wang, Z.J. Heins +740 morecore +2 more sourcesMetformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial [PDF]
, 2009 <br>Background: Metformin reduces cardiovascular risk in patients with type 2 diabetes seemingly independent of lowering blood glucose concentration. We assessed the cardiovascular effects of metformin in individuals without type 2 diabetes.</br&Eddy, Despres, Grundy, Bird, Seifarth, Nathan, Fontbonne, Charles, Holman, Kooy, Knowler, Alberti, Vergeer, Touboul, Liang, Spence, Levey, Meaney, Taylor, Selvin, Boussageon, Sjöström, Shyangdan, de Jager, Bots, Taylor, Boden, Huang, Baigent, Lorenz, Mazzone, Taylor, Lonn, Lexis +33 morecore +5 more sourcesApplications of neuroimaging to disease-modification trials in Alzheimer's disease. [PDF]
, 2009 Critical to development of new therapies for Alzheimer's disease (AD) is the ability to detect clinical or pathological change over time. Clinical outcome measures typically used in therapeutic trials have unfortunately proven to be relatively variable ...Aisen, Paul S, Alzheimer's Disease Neuroimaging Initiative, Brewer, James B, Chen, Kewei, Donohue, Michael, Fleisher, Adam S +5 morecore +2 more sourcesA modified weighted log-rank test for confirmatory trials with a high
proportion of treatment switching [PDF]
, 2020 In confirmatory cancer clinical trials, overall survival (OS) is normally a
primary endpoint in the intention-to-treat (ITT) analysis under regulatory
standards. After the tumor progresses, it is common that patients allocated to
the control group switch Bore, Alexander, Burman, Carl-Fredrik, Jiménez, José L., Niewczas, Julia +3 morecore +2 more sources
