Results 151 to 160 of about 557,108 (293)

Smooth Things Come in Threes: A Diabatic Surrogate Model for Conical Intersection Optimization. [PDF]

J Chem Theory Comput, 2023
Fdez Galván I, Lindh R.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A multiscale topology optimization design framework with data driven surrogate model. [PDF]

Sci Rep
Zhou H, Zhou C.
europepmc   +1 more source

The Application of a Topology Optimization Algorithm Based on the Kriging Surrogate Model in the Mirror Design and Optimization of an Aerial Camera. [PDF]

Sensors (Basel), 2023
Zhao Y, Li L.
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Determination of the parameters of a material constitutive relation using the surrogate model along with dynamic indentation test. [PDF]

Sci Rep
Majzoobi GH, Pourolajal S.
europepmc   +1 more source

ANN based surrogate model for key Physico-chemical effects of cavitation. [PDF]

Ultrason Sonochem, 2023
Ranade NV, Ranade VV.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A General Surrogate Model for CO₂ Flooding Dynamic Prediction Based on Dimensionless Features and Implicit Time. [PDF]

ACS Omega
Li C, Wang X, Yu W, Zhou P.
europepmc   +1 more source

A data-driven reduced-order surrogate model for entire elastoplastic simulations applied to representative volume elements. [PDF]

Sci Rep, 2023
Vijayaraghavan S, Wu L, Noels L, Bordas SPA, Natarajan S, Beex LAA.   +5 more
europepmc   +1 more source